Intense Pulsed Light for Chalazion
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests the effectiveness of a treatment called OptiLIGHT, which uses intense pulsed light (IPL), for removing chalazion (a swollen, painful bump on the eyelid). Researchers aim to determine if this light treatment is safe and effective compared to a sham treatment. It targets individuals who have had a chalazion for less than four weeks. Participants should not have received IPL in the last six months or have other eyelid issues. As an unphased trial, this study provides a unique opportunity to explore a new treatment option for chalazion.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you've used certain medications like Isotretinoin, Tetracycline, Doxycycline, or St. John's Wort within 3 months before screening.
What prior data suggests that this IPL treatment is safe for treating Chalazion?
Research has shown that intense pulsed light (IPL) treatment, such as OptiLIGHT, is generally safe for individuals with chalazion, a common eyelid bump. One study found that IPL treatment significantly reduced the size of chalazia without requiring surgery, and no harmful effects were reported. Another study demonstrated that IPL, when combined with a specific treatment plan, was 96.15% effective, with no observed side effects. This indicates that OptiLIGHT is well-tolerated by patients. Although new treatments always carry some risk, current evidence supports the safety of IPL therapy for chalazion.12345
Why are researchers excited about this trial?
Unlike traditional treatments for chalazion, which often involve warm compresses, steroid injections, or surgical removal, OptiLIGHT uses Intense Pulsed Light (IPL) therapy. This non-invasive approach targets the root causes of chalazion by improving the function of the meibomian glands and reducing inflammation. Researchers are excited about OptiLIGHT because it offers a non-surgical alternative that could potentially provide faster relief with fewer side effects, making it a promising option for patients seeking less invasive treatments.
What evidence suggests that OptiLIGHT is effective for treating Chalazion?
Research has shown that Intense Pulsed Light (IPL) treatment, such as OptiLIGHT, can significantly aid in managing chalazion. In this trial, participants in the study arm will receive active IPL treatment. One study found that using IPL with other treatments succeeded 96.15% of the time, with no negative side effects. Another study found that IPL alone improved conditions in about 74.67% of cases. This indicates that IPL can effectively reduce symptoms and prevent chalazion recurrence. Additionally, IPL has improved eye health in related conditions, supporting its potential benefits for individuals with chalazion.34678
Who Is on the Research Team?
James Chelnis, MD
Principal Investigator
Manhattan Face and Eye
Laura Periman, MD
Principal Investigator
Periman Eye Institute
Are You a Good Fit for This Trial?
This trial is for adults over 18 with a clinical diagnosis of acute chalazion in the left eye, present for up to 4 weeks. Participants must be able to consent and follow study procedures. Excluded are those with recent IPL treatment, poor vision, active sunburn or severe allergies affecting eyes, recent ocular surgery or trauma, eyelid tumors, certain past surgeries like RK or LASIK/SMILE within specific timeframes.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either active IPL treatment or sham IPL treatment
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- OptiLIGHT
Find a Clinic Near You
Who Is Running the Clinical Trial?
Lumenis Be Ltd.
Lead Sponsor