Clinical Trials in Las Vegas, NV

View medical research that is recruiting in Las Vegas, Nevada. Filter by phase, distance, and inclusion criteria to find cutting edge treatments & access premium care.

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Afluria® Quadrivalent

The main purposes of this study are to evaluate the safety and tolerability of mRNA-1345 coadministered with a seasonal influenza vaccine (Afluria® Quadrivalent); to evaluate the impact of coadministered influenza vaccine on the immune response to RSV; and to evaluate the impact of coadmin…

The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of VX-147 in participants aged 18 years and older with apolipoprotein L1 (APOL1)-mediated proteinuric kidney disease.

This is a 16-week, multicenter, randomized, parallel-group, double-blind, controlled study. After assessing eligibility during a screening period of up to 30 days, approximately 320 subjects at least 18 years old who are diagnosed with moderate to severe papulopustular rosacea will be rand…

The reason for this study is to see if the study drug LY3209590 is safe and effective in participants with Type 2 diabetes that have already been treated with basal insulin. The study consists of a 3-week screening/lead-in period, a 78-week treatment period and a 5-week safety follow-up pe…

LumiraDx SARS-CoV-2 & RSV test

A Multicenter Study Conducted to Evaluate the Performance of the LumiraDx SARS-CoV-2 & FLU A/B Test, and LumiraDx SARS-CoV-2 & RSV Test at Point of Care Testing Sites. Subjects presenting with symptoms suggestive of COVID-19 and/or Influenza and/or RSV will be consented and asked to donate…

The purpose of this study is to evaluate the efficacy and safety of MK-0616, an oral PCSK9 inhibitor, in lowering low-density lipoprotein cholesterol (LDL-C) in participants with hypercholesterolemia. The primary hypothesis is that at least one of the four doses of MK-0616 tested in this s…

60 mg PRAX-114 or 40 mg PRAX-114

This trial is comprised of a 4-week randomized, double-blind, placebo-controlled treatment period followed by an optional 8-week open-label extension (OLE) period. This trial will evaluate the efficacy and safety of oral PRAX-114 flexibly dosed at 40 to 60 mg for 4 weeks compared to place…

This Phase 3, multinational, single-arm, multicenter study will evaluate the efficacy and safety of UGN-102 as primary chemoablative therapy in patients with low grade intermediate risk non-muscle-invasive bladder cancer (LG IR NMIBC).

A197 Ophthalmic Solution

The objectives of this trial are to assess the safety, tolerability and efficacy of A197 ophthalmic solution in comparison to a vehicle control in the treatment of subjects with Dry Eye Disease.

The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement (IGA) of CHE score 3 or 4).

Rimegepant 75mg every other day dosing

The purpose of this study is to compare the efficacy and safety of daily and every other day dosing of rimegepant to placebo as a preventive treatment for episodic migraine.

Trigeminal neuralgia (TN), also called "tic douloureux", is the most common form of craniofacial neuropathic pain and is considered the cause of one of the most painful afflictions known in medical practice. This study is designed to evaluate the efficacy and safety of 1.5mg - 3.5mg basim…

Light Adjustable lens (LAL) and Light Delivery Device (LDD)

The primary objective of this study is to conduct a post-approval study which compares the LAL to a monofocal control IOL for safety outcomes.

The primary objectives of this study are to assess the efficacy of vonoprazan (10 mg and 20 mg once daily [QD]) compared to placebo (QD) in relief of heartburn over 4 weeks in participants with NERD.

The purpose of this study is to evaluate the effects of the videogame-like digital therapy on attentional functioning and symptoms in Adults diagnosed with ADHD.

This study is open to adults with chronic kidney disease. People with and without type 2 diabetes can take part in this study. The purpose of this study is to find out whether a medicine called BI 690517 improves kidney function in people with chronic kidney disease when taken alone or in…

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of 50 mg NYX-783 Once Daily Compared to Placebo in Participants with Post-Traumatic Stress Disorder (PTSD)

This is a phase 3 open-label multicenter extension study designed to evaluate the long-term safety and efficacy of Lonapegsomatropin administered once-weekly. The study participants are adults (males and females) with confirmed growth hormone deficiency (GHD) having completed the treatment…

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors and a pathogenic or likely pathogenic tumor PALB2 (tPALB2) mutation.

Study is a randomized, double-blind, double-dummy, parallel-group study evaluating efficacy and safety of revefenacin vs. tiotropium in adults with severe to very severe COPD and suboptimal PIFR.

This FTIH study aims to evaluate the safety, tolerability and PK of the novel investigational Human immunodeficiency virus (HIV)-1 capsid inhibitor VH4004280 in healthy adults. The study will be conducted in 2 parts: Part 1 will investigate single ascending doses (SAD) and Part 2 will inve…

The primary purpose of this study is to evaluate the effect of lumasiran on the percent change in urinary oxalate excretion in patients with recurrent calcium oxalate kidney stone disease.

The purpose of this study is to evaluate the concomitant and non-concomitant use of messenger ribonucleic acid (mRNA) mRNA-1273, the nucleoside-modified mRNA vaccine for active immunization to prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus (S…

Phase 2b study designed to evaluate the efficacy and safety of ASLAN004 in adult patients with moderate-to-severe Atopic Dermatitis (AD) who are candidates for systemic therapy. This study will have 5 treatment arms (4 active and 1 placebo).

This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of subcutaneous lirentelimab (AK002), given monthly for 4 doses, in adult subjects with moderate-to-severe AD inadequately controlled by topical treatments.

This randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of up to 2 treatments of EN3835 vs placebo in participants with plantar fibromatosis.

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic and debilitating urological complex of disorders characterized by symptoms of bladder pain or discomfort, mostly upon bladder filling, and often accompanied by lower urinary tract symptoms (LUTS). This study will assess how …

Study of the contraceptive efficacy, cycle control, safety, and tolerability of MR-100A-01 in approxmiately 1200 women for up to 13 cycles

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis

The purpose of this study is to assess whether galcanezumab is superior to rimegepant in the prevention of migraine in participants with episodic migraine. The study duration will be approximately 6 months.

This study is evaluating whether a vaccine can prevent a first episode of RSV-associated lower respiratory tract disease.

This study is evaluating whether a new iron supplement is safe and tolerable in children and adolescents.

Insulin glargine/Lixisenatide

The purpose of the study is to demonstrate if Soliqua 100/33 improves glycemic control (as measured by Time in Range) and glycemic variability in participants with very uncontrolled (HbA1c ≥ 9%) type 2 Diabetes Mellitus (T2DM) while on at least 2 oral antidiabetic drugs [OADs] with or with…

Sacituzumab Govitecan-hziy

This is a Phase 2, multicenter, open-label, single arm study evaluating the safety and efficacy of trilaciclib administered prior to sacituzumab govitecan-hziy in patients with unresectable, locally advanced or metastatic triple-negative breast cancer (TNBC) who received at least 2 prior t…

Trastuzumab Deruxtecan

This study is evaluating whether a drug called trastuzumab deruxtecan (T-DXd) can be used to treat breast cancer.

The primary objective for this study is to evaluate the effect of adjunctive valbenazine versus placebo on symptoms of schizophrenia in subjects who have inadequate response to antipsychotic treatment.

This study is evaluating whether a drug called aducanumab is more effective than a drug called donanemab in clearing amyloid plaques in people with early symptomatic Alzheimer's disease.

This study is evaluating whether a vaccine that boosts the immune system can be combined with a vaccine that protects against the flu.

The purpose of this study is to evaluate the efficacy and safety of Trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle cream in the treatment of moderate acne vulagris with risk of acne-induced post inflammatory hyperpigmentation (PIH) after 24 weeks of treatment in fa…

This study will be conducted to assess the efficacy, pharmacodynamic (PD), safety, tolerability, and immunogenicity of RGB -14- P compared to US-licensed Prolia® in participants with postmenopausal osteoporosis, in a comparative manner.

This study is evaluating whether a new drug can help people with depression.

The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to 2 hours after investigational medicinal product (IMP) adminis…

The purpose of this study is to evaluate the efficacy of nemolizumab compared to placebo at reducing the intensity of pruritus after a 12-week treatment period in adult hemodialysis participants with severe pruritus.

This study is evaluating whether a new formulation of Humira® can be used to treat psoriasis.

This study is evaluating whether a vaccine can be safely given to healthy people.

This study is evaluating whether a drug can help treat Crohn's disease.

This study is evaluating whether Chronocort® is more effective than immediate-release hydrocortisone replacement therapy in people with Congenital Adrenal Hyperplasia.

This study is evaluating whether a drug called AXS-12 can help people with narcolepsy.

This study is evaluating whether a new drug combination can help people with HIV live longer.

This study is evaluating whether a vaccine made from RNA can be safe and effective in older adults.

Elinzanetant (BAY3427080)

This study is evaluating whether elinzanetant is better than a placebo in treating hot flashes in women who have been through the menopause.

Mirvetuximab soravtansine

This study is evaluating whether a drug called mirvetuximab soravtansine (MIRV) can help treat ovarian cancer.

This study is evaluating whether a drug called EFX can help treat liver disease.

This study is evaluating whether a drug that targets a protein in the lungs can improve lung function in people with COPD.

This study is evaluating whether a vaccine can prevent respiratory syncytial virus (RSV) infections.

This Phase 2 study will evaluate the safety and efficacy of monthly intravenous doses of IXT-m200 in treatment-seeking individuals with methamphetamine (METH) use disorder. The hypothesis are that following an initial relapse, IXT-m200 will reduce the occurrence of stimulant-positive saliv…

This study is evaluating whether a cream can improve the symptoms of atopic dermatitis.

Inclisiran sodium 300 mg

Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).

This study is evaluating whether a treatment for migraine can prevent migraine attacks in adults with episodic migraine.

This study is evaluating whether a drug can prevent blood clots in people with ESRD.

This study is evaluating whether a drug called donanemab can slow the progression of Alzheimer's disease.

This study is evaluating whether a drug called PRAX-944 might be effective in treating essential tremor.

This study is evaluating whether ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation.

This study is evaluating whether a new medicine can control blood sugar levels in people with type 2 diabetes.

This study is evaluating whether a drug called PF-07321332 can help people with COVID-19.

This study is evaluating whether a new drug called pembrolizumab can be used to treat cancer.

XmAb20717 + carboplatin + cabazitaxel

This study is evaluating whether a new drug can improve the survival of people with prostate cancer.

This study is evaluating whether a drug called MLS-101 can help control blood pressure in people with hypertension.

This study is evaluating whether a drug called TPN-101 is safe and well tolerated in people with PSP.

This study is evaluating whether a drug called Lu AG06466 can help reduce spasticity in people with multiple sclerosis.

This study is evaluating whether a new drug can help treat a skin condition called hidradenitis suppurativa.

This study is evaluating whether Adhansia XR is safe for children.

The main purpose of this study is to evaluate the effect of efavaleukin alfa on induction of clinical remission in participants with moderately to severely active ulcerative colitis (UC). Participants will be randomized to receive 1 of 3 efavaleukin alfa doses or placebo during a 12-week …

This study is evaluating whether a drug combination is better than a single drug for treating advanced kidney cancer.

This study is evaluating whether Afrezza is safe and effective in combination with a basal insulin in pediatric subjects with type 1 or type 2 diabetes mellitus.

Cilofexor (CILO)/Firsocostat (FIR)

This study is evaluating whether a combination of a GLP-1 receptor agonist and a drug that reduces inflammation can improve liver fibrosis and NASH.

This study is evaluating whether a new drug called PRAX-114 might be an effective treatment for depression.

FemaSeed Localized Directional Insemination

This study is evaluating whether a new method of artificial insemination is safe and effective.

This Phase 3, randomized, Double-blind, placebo-controlled, 2-arm, parallel-group, multicenter study with randomized withdrawal will evaluate the efficacy, safety, and durability of KBP-5074 in adult participants who have stage 3b/4 chronic kidney disease (CKD) (estimated glomerular filtra…

This study is evaluating whether TAK-105 can help people with nausea and vomiting.

This study is evaluating whether a drug called giredestrant can improve the survival of women with early breast cancer.

This study is evaluating whether a combination of immunotherapy drugs can improve survival for people with bladder cancer.