This trial is testing a combination of drugs to treat leukemia in patients who are older or unable to have standard treatment.
- Acute Myeloid Leukemia
2 Primary · 8 Secondary · Reporting Duration: Up to 3 years
1 Treatment Group
Treatment (uproleselan, azacitidine, venetoclax)
1 of 1
25 Total Participants · 1 Treatment Group
Primary Treatment: Uproleselan · No Placebo Group · Phase 1
Who is running the clinical trial?
Age 18+ · All Participants · 10 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Is there a documented history of research into the therapeutic effects of Uproleselan?
"Currently, there are 345 ongoing trials for Uproleselan with 56 studies in the third phase. Although several of these tests occur out of Edmonton, Alberta; a total of 11265 locations around the globe are running clinical trials involving Uproleselan." - Anonymous Online Contributor
What is the main focus of this investigation?
"According to the research sponsor, GlycoMimetics Incorporated, this trial will be measuring a Recommended Phase II Dose as its primary outcome over an interval of up to thirty days. The secondary outcomes include Duration of CR/CRi and CR/CRh (DoR), Rate of Transfusion-Independence (TI) and Rate of Multiparameter Flow Cytometry (MFC) Measurable/Minimal Residual Disease (MRD)-Negative Complete Remission plus CR with Incomplete Count Recovery. Descriptive statistics such as means, medians and percentiles alongside Exact 95%" - Anonymous Online Contributor
What conditions tend to be treated with Uproleselan?
"Uproleselan is generally used in induction chemotherapy, but can also prove effective for refractory anemias, various forms of leukemia and dysplasias involving multiple lineages." - Anonymous Online Contributor
Are there still opportunities to enroll in this experiment?
"Clinicaltrials.gov shows that this clinical experiment is currently recruiting participants. It was initially uploaded on July 2nd 2021 and was recently revised on August 12th 2022." - Anonymous Online Contributor
What evidence is there to support the safety of Uproleselan when administered to humans?
"There is limited evidence surrounding its safety and efficacy, so Uproleselan received a rating of 1." - Anonymous Online Contributor
How many participants are allowed to join this research endeavor?
"Affirmative. Clinicaltrials.gov documentation indicates that this experiment, which was introduced on July 2nd 2021, is actively recruiting subjects. Approximately 25 people need to be enrolled from 1 medical facility." - Anonymous Online Contributor