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Corticosteroid

Long-Term Use of Relacorilant for Cushing Syndrome

Phase 2
Waitlist Available
Research Sponsored by Corcept Therapeutics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 36 months
Awards & highlights

Study Summary

This trial is to see if it's safe to keep taking relacorilant for people with Cushing syndrome, who have already completed a study and may benefit from continuing treatment.

Who is the study for?
This trial is for patients with Cushing Syndrome who have finished a previous Corcept-sponsored relacorilant study and took their medication at least 80% of the time. They should not have dropped out early, nor should they have uncontrolled thyroid issues, poorly controlled high blood pressure, or severe kidney failure.Check my eligibility
What is being tested?
The trial is testing the long-term safety of a drug called relacorilant in those with endogenous Cushing Syndrome. It's an open-label extension which means everyone knows they are getting relacorilant and there's no placebo group.See study design
What are the potential side effects?
Specific side effects aren't listed here, but since it's about safety, common concerns may include things like nausea, headache, fatigue or other symptoms that could be related to long-term use of the medication.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~36 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 36 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Long-term safety of relacorilant
Other outcome measures
Long-term benefit of relacorilant

Trial Design

1Treatment groups
Experimental Treatment
Group I: relacorilant (CORT125134)Experimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Corcept TherapeuticsLead Sponsor
68 Previous Clinical Trials
6,305 Total Patients Enrolled
12 Trials studying Cushing Syndrome
1,485 Patients Enrolled for Cushing Syndrome
Andreas G Moraitis, MDStudy DirectorCorcept Therapeutics
2 Previous Clinical Trials
50 Total Patients Enrolled
1 Trials studying Cushing Syndrome
35 Patients Enrolled for Cushing Syndrome

Media Library

Relacorilant (Corticosteroid) Clinical Trial Eligibility Overview. Trial Name: NCT03604198 — Phase 2
Cushing Syndrome Research Study Groups: relacorilant (CORT125134)
Cushing Syndrome Clinical Trial 2023: Relacorilant Highlights & Side Effects. Trial Name: NCT03604198 — Phase 2
Relacorilant (Corticosteroid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03604198 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What makes this research project novel?

"There have been 6 trials involving relacorilant completed or underway since 2018 in cities across 12 different countries. The first of these was a Phase 2 clinical trial sponsored by Corcept Therapeutics. It included 75 patients and concluded in 2018. Since then, 9 more studies have taken place."

Answered by AI

Is there a risk of addiction with relacorilant?

"Given that this is a Phase 2 trial, meaning there is only limited data supporting safety but none regarding efficacy, relacorilant was given a score of 2."

Answered by AI

Are there any current openings for volunteers in this experiment?

"Unfortunately, the information available on clinicaltrials.gov suggests that this particular trial is not recruiting patients at this time. Although 1462 other studies are currently underway."

Answered by AI

Are there similar drugs to relacorilant that have been put through clinical trials?

"Presently, there are six trials for relacorilant underway. Two of these studies are in their third and final phase. Most research concerning relacorilant is conducted in Bucuresti, Oklahoma; however, 215 medical centres across the globe are running trials for this medication."

Answered by AI

In how many places is this research being conducted?

"Enrollment for this study is currently underway at 37 hospitals, located in cities such as Wilmington, Fall River and Chicago. If you enroll in the trial, try to select a hospital close to minimize travel time and effort."

Answered by AI

How many individuals are part of this clinical research?

"Unfortunately, this trial is not presently looking for new patients. The listing was first posted on May 7th, 2018 and updated most recently on October 24th, 2022. However, there are 1456 trials actively recruiting patients with cushing syndrome and 6 studies for relacorilant that are currently seeking participants."

Answered by AI
~7 spots leftby Dec 2024