CLINICAL TRIAL

Cognitive Behavioral Therapy for As If Personality

Recruiting · Any Age · All Sexes · Dallas, TX

This study is evaluating whether a therapy session for parents of premature infants can improve outcomes for both the parents and the infants.

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About the trial for As If Personality

Eligible Conditions
Substance-Related Disorders · Infants, Premature · Development, Child · Personality Disorders · Relation, Parent-Child · Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)

Treatment Groups

This trial involves 2 different treatments. Cognitive Behavioral Therapy is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Cognitive Behavioral Therapy
BEHAVIORAL
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.

About The Treatment

Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Behavioral Therapy
2016
Completed Phase 4
~2490

Side Effect Profile for MESH

MESH
Show all side effects
irritability
8%
This histogram enumerates side effects from a completed 2021 Phase 4 trial (NCT04135937) in the MESH ARM group. Side effects include: irritability with 8%.

Eligibility

This trial is for patients born any sex of any age. There are 4 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
is the best predictor of infant survival show original
Born at Parkland Hospital
The baby was born at 30.6 weeks gestation. show original
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: from discharge from Parkland NICU until completion of the study at 6-9 months age
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: from discharge from Parkland NICU until completion of the study at 6-9 months age.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Cognitive Behavioral Therapy will improve 1 primary outcome and 6 secondary outcomes in patients with As If Personality. Measurement will happen over the course of Days will be counted that are spent in the NICU starting from the day of birth of the child which is the admission day to the NICU until discharge day that is documented from Parkland NICU, through study completion, an average of 1 year..

child length of stay in the Parkland NICU (number of days) from birth to discharge from NICU, not including readmissions once first discharge has been accomplished.
DAYS WILL BE COUNTED THAT ARE SPENT IN THE NICU STARTING FROM THE DAY OF BIRTH OF THE CHILD WHICH IS THE ADMISSION DAY TO THE NICU UNTIL DISCHARGE DAY THAT IS DOCUMENTED FROM PARKLAND NICU, THROUGH STUDY COMPLETION, AN AVERAGE OF 1 YEAR.
child length of stay in the Parkland NICU (number of days) from birth to discharge from NICU, not including readmissions once first discharge has been accomplished. Scored in number of total days in the NICU (0 to infinite number). The higher the number, the more lengthy the NICU stay.
differences over time in subsets of Vulnerable Baby Scale (VBSc) scores
MEASUREMENT DIFFERENCES OVER TIME BETWEEN THE TOTAL NUMBER OF QUESTIONS ENDORSED FOR EACH OF THE THREE DIFFERENT QUESTION SUBSETS OF VBSC OF THE PARENTS AT BASELINE OF THE STUDY (33 WEEKS POST-MENSTRUAL AGE) VERSUS AT SIX TO NINE MONTHS OF POST-BIRTH AGE
The VBSc can be broken down into subsets of questions addressing parent 1) thoughts: 2 questions of 10 scale questions, scored 0-2; 2) feelings: 3 questions of 10 scale questions, scored 0-3; and 3) actions/behaviors: 5 questions out of 10 scale questions, scored 0-5. This quantifies the amounts of subsets of the scale that the parent endorses. Higher numbers are markers of more and worse perceptions of child vulnerability in each category of thought, feeling, and action/behavior.
differences over time in parent anxiety scores measured with Beck Anxiety Inventory Scale
MEASURE DIFFERENCES OF THE SCALE'S TOTAL SCORE BETWEEN TIMEPOINTS AT BASELINE OF THE STUDY (33 WEEKS POST-MENSTRUAL AGE) VERSUS AT SIX TO NINE MONTHS OF POST-BIRTH AGE
Beck Anxiety Inventory: This will be used to measure parent anxiety scores, which can be associated with development of VCS. This will be used as a secondary outcome for change over time throughout the study. This is a 21 item questionnaire, measured on a four point likert scale (0-3). Possible scores range from 0-36. A score of greater than 7 suggests anxiety. Scores of 8-15= mild; 16-25= moderate; 26-36= severe.
differences over time in parent depression scores measured with Beck Depression Inventory Scale- 2nd edition.
MEASURE DIFFERENCES OF THE SCALE'S TOTAL SCORE BETWEEN TIMEPOINTS AT BASELINE OF THE STUDY (33 WEEKS POST-MENSTRUAL AGE) VERSUS AT SIX TO NINE MONTHS OF POST-BIRTH AGE
Beck Depression Inventory - 2nd Edition: This will be used to measure parent depression scores, which can be associated with development of VCS. This will be used as a secondary outcome in change over time throughout the study. This is a 21 item questionnaire, measured on a four point likert scale (0-3). A score of greater than 14 signifies depression, with higher scores representing more severe levels of depression. Scores of 0-13= No depression; 14-19= mild; 20-28= moderate; 29-63= severe.
mean value score Vulnerable Baby Scale (VBSc) Score
DIFFERENCE IN THE MEAN VALUE SCORE OF THE VBSC SCORES OF PARENTS AT BASELINE OF THE STUDY (33 WEEKS POST-MENSTRUAL AGE) VERSUS AT SIX TO NINE MONTHS OF POST-BIRTH AGE
Measures parental perceptions of child vulnerability. It has been used for parents with infants as young as 10-12 weeks of age up through 6 months to a year old. It is a 10 question scale, with each question scored on a five point likert scale (1-5). Score range is 10-50. Maximum score of 50 possible. A score of 27 or more was the median score for a sample of medically fragile neonates, and signifies relatively high perceptions of vulnerability. While a score of 23 was the median for a sample of healthy controls and thus reflect a more normal perception of vulnerability (Kerruish et al 2005). The higher the score, the higher the perception of child vulnerability.
Correlation between changes over time in Vulnerable Baby Scale (VBSc) vs. Vulnerable Child Scale (VCSc) scores
MEASUREMENT DIFFERENCES OF SCORES FROM BASELINE OF THE STUDY (33 WEEKS POST-MENSTRUAL AGE) VERSUS AT SIX TO NINE MONTHS OF POST-BIRTH AGE
The VCSc is the most frequently and widely used scale to measure parent perceptions of vulnerability and Vulnerable Child Syndrome (VCS). It was modified by the author from the original 12 question scale to an 8 question scale. The modified scale has higher internal validity and consistency (Forsyth et al 1996). This scale was intended for and has been used for children aged mostly from 6 months to 8 years of age or older. Each question is scored on a four point likert scale (0-3). A total score of 0 to 24 is possible, the higher the score the more perceptions of vulnerability. A score of greater than 10 signifies high perceptions of vulnerability. See above for VBSc description.
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Who is running the study

Principal Investigator
M. H.
Margaret Hoge, Clinical Fellow
University of Texas Southwestern Medical Center

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of as if personality?

The 'as if' paradigm highlights a variety of behavioral patterns that reflect [an individual's personality characteristics], in particular the individual's tendency to respond in ways characteristic of individuals who have high 'openness/conscientiousness' tendencies. This 'as if' view of personality is rooted in the notion of self-fulfilling prophecy.

Anonymous Patient Answer

What are common treatments for as if personality?

A wide variety of treatment modalities can be utilized to treat as if. These treatment modalities include psychotherapy, biological therapy, and surgery. In addition, many of the psychotherapeutic treatments can be used in conjunction with biological treatment. The treatment approach varies with each of the three components of as if personality and the various levels and types of treatment available. The most common methods are psychotherapy and psychotherapy with surgery. Other treatment options include biology, therapy with drugs, and medical therapy. No particular treatment modality is more commonly used than the other, but most commonly used are psychotherapy and biological therapy.

Anonymous Patient Answer

Can as if personality be cured?

Personality is influenced by personality characteristics before treatment is applied. This relationship implies that treatment to change personality may be of little or no benefit in the long term.

Anonymous Patient Answer

How many people get as if personality a year in the United States?

This is the first study to quantify associations between personality factors and major mental disorders (i.e., depression and anxiety disorders), suggesting that these may be best conceptualized in terms of personality characteristics. Results from a recent paper highlight the need to broaden the research focus of personality psychology, which might have implications for both psychological interventions and research design.

Anonymous Patient Answer

What is as if personality?

As individuals aged 70 and over, on the entire sample and for white men, there are more as if personalities than it is for white women. The study does not clarify whether the finding exists for all individuals in the sample or it is only some of them.\n

Anonymous Patient Answer

What causes as if personality?

Results from a recent clinical trial reveal that some personality traits that people report do have a measurable biological basis, and some personality traits may not be as readily identified as other attributes of personality.

Anonymous Patient Answer

Does as if personality run in families?

Although most as if questions are not answered, the general theme of the interview was the influence of NFTs on the development and formation of the personality of a person. Recent findings could be useful in the search for a more in-depth understanding of the personality of someone with NFTs and in counseling of the patients suffering from NFTs.

Anonymous Patient Answer

What is the average age someone gets as if personality?

The average age one gets as if personality and the average age of one becomes as if personality have been the same thing for many years, but it is different in different societies. The average age the person dies as if personality will differ for future generations.

Anonymous Patient Answer

Does cognitive behavioral therapy improve quality of life for those with as if personality?

Results from a recent paper of this study demonstrate that cognitive-behavioral therapy led to improvements in multiple quality-of-life parameters. In this sample, patients with ASPD presented with increased levels of depressive symptoms. It is possible that ASPD may impact the ability of participants to attend to treatment-sensitive measures of quality of life.

Anonymous Patient Answer

Is cognitive behavioral therapy typically used in combination with any other treatments?

Cognitive behavioral therapy appears to be often used in combination with other psychosocial treatments. There is the need to identify these combinations of psychosocial treatments to gain further clinical insights that might improve the effects of treatments in these therapies.

Anonymous Patient Answer

What are the latest developments in cognitive behavioral therapy for therapeutic use?

Recent studies indicate that cognitive behavior therapy can be used effectively to treat major depression and other somatic symptom disorders. The CBT model is promising for treating anxiety disorders and substance abuse disorders.

Anonymous Patient Answer

Have there been any new discoveries for treating as if personality?

Data from a recent study of this present study would suggest that patients with BPD are not different from non-BDD patients in terms of personality profiles. Data from a recent study indicate that BDD patients and BPD patients are similar in terms of personality profiles. However, BPD patients do report a more somatic approach to physical treatments.

Anonymous Patient Answer
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