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Study Summary
This trial will test the safety of a new drug for people with cancer that has spread or gotten worse. The drug will be given alone and with other cancer drugs.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have a condition or had surgery that affects how my body absorbs food.I have not had major surgery in the last 2 weeks.I have lung problems that make it hard for me to breathe.I have an advanced cancer that hasn't responded to treatment.I haven't had cancer treatment or experimental therapy in the last 28 days or 6 weeks for certain drugs.I have not had cancer, except for treatable in situ types, in the last 2 years.I have or had hepatitis B or C, but it's not active now.I am on medication for seizures.Your heart's electrical activity takes longer than normal to recharge after a beat.I have severe heart issues or had a heart attack in the last 6 months.I do not have any serious infections that need treatment with medication.Your oxygen level while resting is 90% or lower when breathing normal air.You have had allergic reactions to similar medicines or treatments in the past.I have brain metastases treated and am not on high-dose steroids.
- Group 1: TP-1454
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this study currently have open enrollment?
"According to clinicaltrials.gov, this particular study is not open for recruitment at the moment and has been edited for the final time on November 18th 2022. Nevertheless, 1433 other trials are still accepting participants."
What are the potential adverse effects of TP-1454 monotherapy?
"There is limited clinical data establishing TP-1454 monotherapy's safety, thus it recieved a rating of 1."
In what areas is the experiment being conducted?
"This trial has 9 locations that are currently running, including the Norris Cancer Center at University of Southern California and Hoag Memorial Hospital in Los Angeles, Texas Oncology Baylor Sammons Cancer Center in Dallas, Mayo Clinic Arizona in Phoenix, plus 6 other sites."
Who else is applying?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Why did patients apply to this trial?
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