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Brain Imaging for Post-Heart Attack Inflammation
Study Summary
This trial will test if an investigational drug can show brain inflammation after a heart attack. It may help develop new treatments to protect the brain.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Media Library
- I am admitted to UAB Hospital for a severe heart attack and treated with PCI, or I am undergoing elective PCI.I am 21 years old or older.I have had heart bypass surgery in the past.You have had a serious head injury that caused you to lose consciousness for more than 30 minutes or have a seizure.I speak English and have completed at least 8th grade.My genetic test shows I have a specific marker (rs6971) for TSPO ligands.I have had a heart attack before.I have had angioplasty or a stent placed in my coronary artery.You are currently breastfeeding.You cannot have an MRI for medical reasons.I have severe anemia.I have been diagnosed with major depression.I have been diagnosed with dementia.My genetic test shows I have a low affinity for TSPO ligands.
- Group 1: undergoing elective percutaneous coronary intervention
- Group 2: Recent Myocardial Infarction
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants are currently enrolled in this research initiative?
"Appropriately, clinicaltrials.gov states that this experiment is currently searching for volunteers; it was initially posted on October 17th 2019 and last updated on August 25th 2022. The research requires 20 participants to be sourced from 1 location."
What potential risks are associated with the use of [18F]DPA-714-PET/MRI?
"[18F]DPA-714-PET/MRI's safety rating is a 1 due to the fact that this Phase 1 trial has minimal data corroborating its efficacy and security."
Is the enrollment phase of this trial ongoing?
"According to clinicaltrials.gov, this investigation is actively recruiting participants as of August 25th 2022. The trial was first published on October 17th 2019."
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