Your session is about to expire
← Back to Search
Procedure
Speech Therapy + tDCS for Aphasia
N/A
Waitlist Available
Led By Maya Henry, PhD
Research Sponsored by University of Texas at Austin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Score of 20 or higher on the Mini-Mental State Examination
Meets diagnostic criteria for PPA
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from pre-treatment to one month and three months after onset of treatment in each phase (stimulation and sham)
Awards & highlights
Study Summary
This trial aims to improve quality of life for people with PPA by combining speech-language telerehabilitation and tailored neuromodulatory treatment in their homes.
Who is the study for?
This trial is for adults with Primary Progressive Aphasia who can think clearly enough (score of 20+ on a mental state exam), see and hear well (with aids if needed), undergo an MRI, have internet access, and a partner to help them through the study. It's not for those with other neurological issues, history of stroke/epilepsy/severe brain injury, or contraindications for tDCS/MRI.Check my eligibility
What is being tested?
The trial tests whether home-based brain stimulation paired with speech-language therapy via video call helps people with different types of PPA. Participants will receive either real or sham brain stimulation while engaging in language exercises designed to improve communication.See study design
What are the potential side effects?
Transcranial Direct Current Stimulation may cause mild side effects like itching, tingling at the electrode site, headache, fatigue or nausea. However, it's generally considered safe and these sensations typically fade after the session.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
My mental state score is 20 or higher.
Select...
I have been diagnosed with primary progressive aphasia.
Select...
I have been diagnosed with a specific type of primary progressive aphasia.
Select...
I am willing and able to have an MRI scan of my brain.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ change from pre-treatment to one month and three months after onset of treatment in each phase (stimulation and sham)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from pre-treatment to one month and three months after onset of treatment in each phase (stimulation and sham)
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
RS-LRT arm: Change in spoken naming
RS-VISTA arm: Change in script production accuracy
Secondary outcome measures
Care Partner Survey
Change on Aphasia Impact Questionnaire
Change on Communication Confidence Rating Scale for Aphasia
+2 moreTrial Design
2Treatment groups
Experimental Treatment
Group I: RS-VISTAExperimental Treatment3 Interventions
Group II: RS-LRTExperimental Treatment3 Interventions
Find a Location
Who is running the clinical trial?
University of California, San FranciscoOTHER
2,503 Previous Clinical Trials
15,236,645 Total Patients Enrolled
University of Texas at AustinLead Sponsor
350 Previous Clinical Trials
80,974 Total Patients Enrolled
Maya Henry, PhDPrincipal InvestigatorUniversity of Texas at Austin
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- My mental state score is 20 or higher.I don't have a history of seizures, head injuries, severe migraines, metal implants in my head, chronic skin problems, or a pacemaker. I am not pregnant.I have been diagnosed with primary progressive aphasia.I have been diagnosed with a specific type of primary progressive aphasia.You do not have the specific type of PPA that the study is focusing on.I can hear and see well enough, with aids if necessary.You have a score lower than 20 on a test that checks memory and thinking skills.My speech and language issues are due to a different neurological condition.I have had a stroke, epilepsy, or significant brain injury.I am willing and able to have an MRI scan of my brain.
Research Study Groups:
This trial has the following groups:- Group 1: RS-VISTA
- Group 2: RS-LRT
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is this experiment currently enrolling participants?
"Data from clinicaltrials.gov reveals that this medical study is currently seeking participants, and was initially posted on July 1st 2023 with the most recent update occurring on June 2nd of the same year."
Answered by AI
How many individuals is the trial organization recruiting for participation?
"Affirmative. Clinicaltrials.gov lists this experiment as actively recruiting, with the initial posting dated July 1st 2023 and last update on June 2nd 2023. This investigation requires 10 participants from two separate medical sites."
Answered by AI
What are the essential objectives of this medical experiment?
"The primary benchmark of success for this clinical trial is the change in script production accuracy between pre-treatment observations and those taken one month and three months after treatment begins. Additional metrics include shifts in Aphasia Impact Questionnaire scores, patient/client satisfaction as measured by a Client Satisfaction Questionnaire, and participants' perceptions regarding remote tdcs via an RS-tDCS Survey."
Answered by AI
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger