Supportive Weight Management for Obesity

JE
CI
CI
Overseen ByCorrine I. Voils, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: VA Office of Research and Development
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether support from a household member can help Veterans lose weight more effectively in a weight management program. It examines two groups: one where Veterans participate with a supportive adult, such as a spouse or friend (dyadic intervention), and another where they participate alone (veteran-only intervention). The trial suits Veterans with a BMI of 30 or more who want to lose weight and live with someone willing to provide support. Participants must have visited a VA primary care provider in the past year and have internet access. As an unphased trial, this study offers Veterans a unique opportunity to explore innovative weight management strategies with the support of a loved one.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are currently using weight loss medications.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that including a partner in weight-loss programs, known as dyadic intervention, can be safe and may enhance results. One study examined how individuals and their partners collaborated to lose weight. It found that partner involvement was generally well-received, with no major safety concerns reported.

Another study focused on improving communication and support among family members for healthier habits. This approach also revealed no significant safety issues. While weight loss results can vary, having a support person does not appear to add any risk.

For those considering joining a trial with a dyadic intervention, current research suggests it is safe. The main goal is to work together with a partner to support each other’s weight-loss goals.12345

Why are researchers excited about this trial?

Researchers are excited about these interventions for obesity because they focus on integrating social support, which isn't commonly emphasized in traditional weight management programs. The dyadic intervention involves veterans working together with a support person, which may enhance motivation and accountability. In contrast, the veteran-only intervention allows for individual focus, which could provide insights into the effectiveness of personal responsibility in weight management. These approaches aim to explore how social dynamics and individual effort can impact weight loss success, offering potentially new strategies for managing obesity beyond standard diet and exercise plans.

What evidence suggests that this trial's treatments could be effective for weight management?

Research has shown that having a support person in weight-loss programs can increase their effectiveness. In this trial, participants in the Dyadic intervention arm, where both the Veteran and their support person join the MOVE! program, may experience enhanced outcomes. One study found that when both a participant and their partner at home joined the program, it led to better results. Another study showed that one person's progress could significantly influence the other's, especially in the early stages. Additionally, the "Live Well" program highlighted that community-based approaches, which often include social support, can successfully tackle obesity. These findings suggest that having a support person join the Veteran in a weight management program might improve weight loss results. Meanwhile, the Veteran-only intervention arm will assess the effectiveness of the MOVE! program when Veterans participate alone.16789

Who Is on the Research Team?

CI

Corrine I. Voils, PhD

Principal Investigator

William S. Middleton Memorial Veterans Hospital, Madison, WI

Are You a Good Fit for This Trial?

This trial is for Veterans with obesity who are at least 18 years old, have a BMI of 30 kg/m2 or higher, and have seen a VA primary care provider in the past year. They must live with an adult willing to support their weight loss journey, be able to stand unassisted for weigh-ins, and not be involved in other lifestyle change programs. Pregnant individuals or those planning pregnancy soon are excluded.

Inclusion Criteria

My partner is willing to join, speaks English, and passed a short memory test.

Exclusion Criteria

Patient exclusion criteria: active dementia or substance abuse, history of bariatric surgery, current participation in a research or clinical program focusing on lifestyle change, pregnancy, breastfeeding, or planning to become pregnant in the next 18 months, weight loss 10 lb in the month prior to screening, residing in a nursing home or receiving long-term home health care, unable to control what food is purchased and / or served, impaired hearing, current use of weight loss medications, chronic or unstable illness that would limit ability to participate (e.g., recent hospitalization)
My partner does not have dementia, substance abuse issues, live in a nursing home, have hearing problems, or any unstable illness.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a weight management program, either alone or with a support person, delivered via a secure video platform

72 weeks
Remote assessments at baseline, weeks 24, 48, and 72

Follow-up

Participants are monitored for weight and quality of life outcomes after the treatment phase

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Dyadic intervention
  • Veteran-only intervention
Trial Overview The study is testing if having social support from someone they live with helps Veterans lose more weight in a management program compared to going it alone. It compares two approaches: one where the Veteran works together with their cohabitant (dyadic intervention) and another where only the Veteran participates (Veteran-only intervention).
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Dyadic interventionExperimental Treatment1 Intervention
Group II: Veteran-only interventionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

VA Office of Research and Development

Lead Sponsor

Trials
1,691
Recruited
3,759,000+

Published Research Related to This Trial

A survey of 450 former participants in a community-based weight management program revealed that early discussions about weight loss perceptions are crucial for successful weight loss maintenance (WLM).
To maintain weight loss after a program, individuals should focus on specific behaviors like weekly weighing, limiting evening snacks, controlling portion sizes, and engaging in daily physical activity.
Predictors of weight loss maintenance following an insurance-sponsored weight management program.Abildso, CG., Schmid, O., Byrd, M., et al.[2021]

Citations

Dyadic Dynamics in a Randomized Weight-Loss InterventionThrough a reanalysis of data from a randomized weight-loss intervention, this study compared dyadic dynamics in intervention participants and in-home partners.
Evaluation of Dyadic Changes of Parent-Child Weight Loss ...The lagged effect from child-to-parent BMI was also positive and statistically significant during the first 10 sessions (B=0.029, p<0.01; d=0.154), but the ...
Study Details | NCT04036331 | Dyad Plus Effectiveness/ ...The purpose of this research is to determine the effectiveness of a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, ...
Results from “Live Well”, a randomized controlled community ...Findings from Live Well demonstrate the viability of utilizing a CBPR approach to address overweight and obesity among immigrant mothers.
Effects of the dyadic FirstStep2Health intervention on ...Although not statistically significant, the intervention showed positive effects on improving parents' F/V intake, parental support on healthy eating and ...
Weight Management in Mothers and Adult Daughters ...The adapted intervention will focus on improving dyadic communication and collaboration for providing reciprocal support for healthy eating and physical ...
Dyadic reports of weight control practices, sedentary ...The objective of this study was to describe the dyadic reports of weight control practices, sedentary and screen time behaviors, and family functioning and ...
NCT03811743 | A Coordinated Parent/Child Dyad Weight ...The purpose of this research is to develop a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, ...
a randomized controlled trial to evaluate 24-month weight loss ...Partner support is associated with better weight loss outcomes in observational studies, but randomized trials show mixed results for including partners.
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