Diazepam for Syndrome

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Syndrome
Diazepam - Drug
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test whether it's possible to manage alcohol withdrawal symptoms remotely, and whether patients are satisfied with this method.

Treatment Effectiveness

Study Objectives

2 Primary · 6 Secondary · Reporting Duration: 3-5 day treatment period

3-5 day treatment period
Diazepam dose
Duration of active withdrawal treatment
Requirement of benzodiazepines
Retention in treatment
Transfer to a higher level of care
Withdrawal severity
Week 1
Patient satisfaction with the telemedicine platform
Patient satisfaction with the treatment protocol

Trial Safety

Trial Design

1 Treatment Group

Symptom-triggered diazepam treatment
1 of 1
Experimental Treatment

30 Total Participants · 1 Treatment Group

Primary Treatment: Diazepam · No Placebo Group · N/A

Symptom-triggered diazepam treatment
Drug
Experimental Group · 1 Intervention: Diazepam · Intervention Types: Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Diazepam
FDA approved

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 3-5 day treatment period

Who is running the clinical trial?

Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,221 Previous Clinical Trials
24,403,227 Total Patients Enrolled
30 Trials studying Syndrome
21,414 Patients Enrolled for Syndrome
Ontario Ministry of Health and Long Term CareOTHER_GOV
91 Previous Clinical Trials
108,776 Total Patients Enrolled
Centre for Addiction and Mental HealthLead Sponsor
318 Previous Clinical Trials
75,858 Total Patients Enrolled
Matthew Sloan, MD, MScPrincipal InvestigatorCentre for Addiction and Mental Health

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You must be actively using alcohol.
You have previously met criteria for alcohol withdrawal.
Aim to achieve at least 30 days of abstinence as a treatment goal following initiation of remote alcohol withdrawal management.
You are able to stay at an address within 2-hours travelling distance from the Centre for Addiction and Mental Health for the entire duration of the remote withdrawal procedure.
You are enrolled in the Ontario Health Insurance Plan (OHIP).

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 2nd, 2021

Last Reviewed: October 17th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.