CSPOT for Heart Failure
(CSPOT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing three different methods to help patients with irregular heartbeats. It uses special devices to send electrical signals that make the heart beat more regularly. The goal is to find out which method works best and is safest.
Do I need to stop my current medications for the CSPOT trial?
The trial protocol does not specify whether you need to stop taking your current medications. However, if you are on continuous infusion therapy for heart failure, you may not be eligible to participate.
Is CSPOT for Heart Failure generally safe for humans?
How is the CSPOT treatment for heart failure different from other treatments?
Conduction System Pacing Optimized Therapy (CSPOT) is unique because it focuses on pacing the heart's natural conduction system, which can lead to more natural heartbeats compared to traditional methods that pace the heart from the outside. This approach may improve heart function and synchronization more effectively than conventional cardiac resynchronization therapy (CRT), especially in patients with heart failure.678910
What data supports the effectiveness of the treatment CSPOT for Heart Failure?
Are You a Good Fit for This Trial?
This trial is for adults with heart failure who need a new or upgraded CRT device and can follow the study plan. They should have specific types of irregular heartbeats but not persistent AF/AFL, severe valve issues, recent heart attacks, or certain other conditions.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Device Implantation and Acute Pacing Protocol
Participants undergo CSPOT lead placement, acute pacing protocol with various configurations, and device implantation
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Conduction system pacing-only configuration
- Conduction System Pacing Optimized Therapy (CSPOT) configuration
- Left ventricular coronary sinus configuration
Find a Clinic Near You
Who Is Running the Clinical Trial?
Medtronic Cardiac Rhythm and Heart Failure
Lead Sponsor
Geoff Martha
Medtronic Cardiac Rhythm and Heart Failure
Chief Executive Officer since 2020
MBA from University of Minnesota
Dr. Kweli Thompson
Medtronic Cardiac Rhythm and Heart Failure
Chief Medical Officer since 2022
MD from Harvard Medical School