← Back to Search

Immunosuppressant

Envarsus XR for Delayed Graft Function (E-DGF Trial)

Phase 4
Waitlist Available
Led By Sandesh Paranjuli, MBBS
Research Sponsored by University of Wisconsin, Madison
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 months post transplant
Awards & highlights

E-DGF Trial Summary

This trial is testing a new extended release tacrolimus designed to deliver the drug more consistently and avoid large fluctuations in tacrolimus levels. It is expected that patients who receive Envarsus XR will have more stable tacrolimus levels and recover from DGF more quickly than those who receive immediate release tacrolimus.

E-DGF Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 months post transplant
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 months post transplant for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Days Needed to Recover From Delayed Graft Function (DGF)
Secondary outcome measures
Number of Tacrolimus or Envarsus XR Dose Adjustments Required During the Period of DGF
Other outcome measures
Number of Participants Experiencing Related Adverse Events

E-DGF Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ExperimentalExperimental Treatment1 Intervention
Envarsus XR
Group II: Standard of CareActive Control1 Intervention
Standard of Care Tacrolimus
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Envarsus XR
2017
Completed Phase 4
~230

Find a Location

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,184 Previous Clinical Trials
3,169,368 Total Patients Enrolled
3 Trials studying Delayed Graft Function
201 Patients Enrolled for Delayed Graft Function
Veloxis PharmaceuticalsIndustry Sponsor
41 Previous Clinical Trials
3,046 Total Patients Enrolled
Sandesh Paranjuli, MBBSPrincipal InvestigatorUniversity of Wisconsin School of Medicine and Public Health, Madison

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Envarsus in Delayed Graft Function (E-DGF)
2019. "Envarsus in Delayed Graft Function (E-DGF)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03864926.
~16 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top