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Magnetic Resonance Elastography for Liver Cancer

N/A
Recruiting
Led By Priya Bhosale
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Liver cancer
Available tumor and liver parenchyma tissue (biopsy-proven HCC)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 18 months
Awards & highlights

Study Summary

This trial is testing how well an investigational scan works with standard imaging to detect response to treatment in patients with liver cancer.

Who is the study for?
This trial is for patients with advanced liver cancer that has spread, who have biopsy-proven hepatocellular carcinoma (HCC) and can provide tissue samples. Participants must not have any conditions that make MRI unsafe, like metal implants or fragments in the body, and cannot be pregnant. They must also be able to give informed consent.Check my eligibility
What is being tested?
The study is testing a new type of scan called Magnetic Resonance Elastography (MRE), alongside standard MRI scans, to see if they can better detect how well treatments are working in patients with advanced liver cancer.See study design
What are the potential side effects?
Since MRE and MRI are imaging techniques rather than drugs or surgeries, side effects are minimal but may include discomfort from lying still during the procedure or anxiety in confined spaces (claustrophobia).

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have liver cancer.
Select...
I have biopsy-proven liver cancer tissue available for testing.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~18 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in magnetic resonance elastography (MRE) liver tumor stiffness
Change in percent non-viable/necrotic tumor
Secondary outcome measures
Change in tumor size and enhancement
Overall survival
Time to tumor progression

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic (MRI/MRE)Experimental Treatment2 Interventions
Patients undergo standard of care MRI and MRE over 30-90 minutes within 5 days of liver biopsy before receiving any medical treatment for HCC, at 6 weeks after medical treatment for HCC, and then every 12 weeks for up to 24 months.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Magnetic Resonance Imaging
2017
Completed Phase 3
~1180

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,627 Previous Clinical Trials
40,927,297 Total Patients Enrolled
104 Trials studying Liver Cancer
26,668 Patients Enrolled for Liver Cancer
M.D. Anderson Cancer CenterLead Sponsor
2,962 Previous Clinical Trials
1,803,306 Total Patients Enrolled
22 Trials studying Liver Cancer
9,411 Patients Enrolled for Liver Cancer
Priya BhosalePrincipal InvestigatorM.D. Anderson Cancer Center
1 Previous Clinical Trials

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible to still join this experiment?

"Affirmative. Per the clinicaltrials.gov listing, this medical trial is still actively recruiting participants since its inception on June 11th 2019 and last edit made on June 6th 2022. The study seeks to enrol 50 people at a single site."

Answered by AI

How many individuals are currently participating in this clinical investigation?

"Affirmative. The clinical trial, which was initially announced on June 11th 2019, is still receiving applicants as indicated by the information found on clinicaltrials.gov. Altogether 50 individuals need to be recruited at a singular site."

Answered by AI
~9 spots leftby Apr 2025