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Botulinum Toxin A for Peripheral Neuropathy
Study Summary
This trial is examining whether a toxin commonly used to treat muscle spasms can also help relieve nerve pain caused by chemotherapy.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have nerve damage not caused by chemotherapy.I have breast cancer and have been treated with taxane-based chemotherapy.I have breast cancer and have been treated with taxane-based chemotherapy.I have nerve pain that started after my chemotherapy within 6 months.My pain is likely nerve-related, scoring over 4 on a specific pain scale.I am not pregnant, breastfeeding, nor planning to become pregnant soon.I am currently on chemotherapy or finished it within the last 6 months.I am on hemodialysis for end-stage kidney disease.I haven't changed my neuropathic pain medication in the last month.I have not received Botulinum Toxin A treatment in the last 6 months.I have weakness or muscle loss in my hands or feet.I have an infection where I would get the injection.I am over 18 years old.I started experiencing nerve pain within 6 months after my chemotherapy.
- Group 1: IncobotulinumtoxinA
- Group 2: saline control
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many patients are enrolled in this study?
"Yes, the most recent information available on clinicaltrials.gov shows that this study is actively looking for patients to enroll. The original posting was on July 8th, 2020 and the last update was December 21st, 2021. So far, 40 people have been enrolled at a single site."
What does the scientific community know about IncobotulinumtoxinA from past research?
"Currently, there are 68 ongoing clinical trials investigating IncobotulinumtoxinA with 22 trials in Phase 3. While most of the clinical trials for IncobotulinumtoxinA are based in Farmington Hills, Michigan, there are 761 locations operating clinical trials for IncobotulinumtoxinA."
Are we still able to enroll participants for this research project?
"This trial, which is currently recruiting patients, was first posted on July 8th 2020. The listing was last updated on December 21st 2021."
For what purpose is IncobotulinumtoxinA commonly prescribed?
"IncobotulinumtoxinA is commonly used to ameliorate urinary incontinence but can also help patients with conditions such as spinal cord, botox, and overactive bladder syndrome."
Does IncobotulinumtoxinA carry any risks for patients?
"There is some data suggesting IncobotulinumtoxinA is safe, but none that it is effective. Therefore, we've given it a score of 2."
Who else is applying?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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