← Back to Search

Antihistamine

Doxepin for Hives

Phase 3
Recruiting
Research Sponsored by State University of New York - Upstate Medical University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 hour after med administration, 2 hours after administration, and prior to discharge
Awards & highlights

Study Summary

This trial compares the effectiveness of doxepin versus diphenhydramine in treating isolated urticaria in the emergency department.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 hour after med administration, 2 hours after administration, and prior to discharge
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 hour after med administration, 2 hours after administration, and prior to discharge for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Improvement of urticaria

Side effects data

From 2010 Phase 4 trial • 44 Patients • NCT00465972
13%
dry mouth
4%
sedation
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo
Temazepam

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: DoxepinExperimental Treatment1 Intervention
25mg PO one time
Group II: DiphenhydramineActive Control1 Intervention
50mg PO one time
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Doxepin
2018
Completed Phase 4
~560

Find a Location

Who is running the clinical trial?

State University of New York - Upstate Medical UniversityLead Sponsor
172 Previous Clinical Trials
27,172 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are we seeking volunteers who meet the age requirement for this experiment?

"For this particular clinical trial, only patients aged 18 to 65 can enroll. If you are not within this age range, there are 16 other clinical trials you may be eligible for."

Answered by AI

How many research subjects are you enrolling in this investigation?

"Yes, you are correct. The clinical trial is still recruiting patients and was last updated on 5/17/2022. This study is looking for 160 participants from a single site."

Answered by AI

Are there negative consequences associated with Doxepin?

"Doxepin has received a safety score of 3. This means that while it is still in clinical trials, there is evidence of its efficacy and multiple rounds of data supporting its safety."

Answered by AI

What medical prerequisites are necessary in order to enroll in this research project?

"Researchers are looking for around 160 adult patients that have urticaria in order to study the long-term effects of the condition."

Answered by AI

How does Doxepin's trial history compare to similar drugs?

"As of now, there are 34 separate clinical trials researching Doxepin. Of these, 9 have progressed to Phase 3. though most of the Doxepin studies are based in Birmingham, Alabama, there are 801 total locations running these experiments."

Answered by AI

For what conditions is Doxepin most commonly prescribed?

"Doxepin is often given to patients suffering from bronchitis, but it can also provide relief for conditions such as chronic coughing, difficulty sleeping, and skin inflammation."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Using Doxepin for Urticaria
David Andonian 2022. "Using Doxepin for Urticaria". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05115136.
~55 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top