Peak Expiratory Flow Rate (PEFR) for Asthma

Hennepin County Medical Center, Minneapolis, MN
AsthmaPeak Expiratory Flow Rate (PEFR) - Other
16 - 55
All Sexes
What conditions do you have?

Study Summary

This trial will study the effects of two different methods of managing asthma exacerbations in the emergency department.

Eligible Conditions
  • Asthma

Treatment Effectiveness

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: 150 minutes

12 hours
ED Length of Stay
Hospitalization during index encounter
Number of nebulized treatments with short-acting beta antagonists (SABA)
150 minutes
Adequate control of asthma symptoms within 150 minutes
72 hours
Relapse following discharge within 72 hours

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

PEFR Guided Management
1 of 2
Non-PEFR Guided Management
1 of 2

Experimental Treatment

220 Total Participants · 2 Treatment Groups

Primary Treatment: Peak Expiratory Flow Rate (PEFR) · No Placebo Group · N/A

PEFR Guided Management
Experimental Group · 1 Intervention: Peak Expiratory Flow Rate (PEFR) · Intervention Types: Other
Non-PEFR Guided Management
Experimental Group · 1 Intervention: Standard Clinical Judgement · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 150 minutes

Who is running the clinical trial?

Hennepin Healthcare Research InstituteLead Sponsor
86 Previous Clinical Trials
76,415 Total Patients Enrolled

Eligibility Criteria

Age 16 - 55 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have asthma and need to use nebulized albuterol treatments at least twice.
You have sudden and severe symptoms of asthma, such as difficulty breathing, coughing, wheezing, and tightness in the chest.

Who else is applying?

What state do they live in?
What site did they apply to?
Hennepin County Medical Center100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

Frequently Asked Questions

Are octogenarians being considered as participants in this experimentation?

"This clinical trial mandates that participants are between 16 and 55 years of age. Elsewhere, 155 trials open to applicants under the legal age of consent exist while 358 studies accept individuals above 65 years old." - Anonymous Online Contributor

Unverified Answer

How many participants are receiving care for this research effort?

"Yes, indeed.'s records reveal that this clinical trial began recruitment on January 19th 2018 and was most recently updated on December 5th 2022. 220 volunteers will be accepted across a single location for the experiment." - Anonymous Online Contributor

Unverified Answer

What are the eligibility requirements for participating in this clinical research?

"This trial requires 220 volunteers suffering from asthma, aged between 16 and 55. More specifically, enrolment must start 15 minutes after being admitted to the ED and participants need to have a functioning phone number in order for our team to contact them 72 hours post-encounter." - Anonymous Online Contributor

Unverified Answer

Are health care professionals currently accepting volunteers for this clinical experiment?

"Data on reveals that this trial, which has been ongoing since January 19th 2018, is actively seeking candidates. The study was last adjusted on December 5th 2022." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.