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Peak Expiratory Flow Rate (PEFR) for Asthma

N/A
Waitlist Available
Research Sponsored by Hennepin Healthcare Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Presumed diagnosis of asthma, requiring at least 2 nebulized albuterol treatments
Presenting with acute asthma exacerbation defined as acute or subacute episodes of progressively worsening shortness of breath, cough, wheezing, and chest tightness, or some combination of these symptoms
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 150 minutes
Awards & highlights

Study Summary

This trial will study the effects of two different methods of managing asthma exacerbations in the emergency department.

Eligible Conditions
  • Asthma

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have asthma and need to use nebulized albuterol treatments at least twice.
Select...
You have sudden and severe symptoms of asthma, such as difficulty breathing, coughing, wheezing, and tightness in the chest.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~150 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 150 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adequate control of asthma symptoms within 150 minutes
Secondary outcome measures
ED Length of Stay
Hospitalization during index encounter
Number of nebulized treatments with short-acting beta antagonists (SABA)
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: PEFR Guided ManagementExperimental Treatment1 Intervention
Peak Expiratory Flow Rate (PEFR) Patients in this group will perform PEFR testing every 30 minutes and this data along with the National Asthma Prevention and Education Program guidelines will be considered by primary ED medical providers in the management of this group.
Group II: Non-PEFR Guided ManagementExperimental Treatment1 Intervention
Standard Clinical Judgement Patients in this group will receive management based on primary medical provider's clinical judgement.

Find a Location

Who is running the clinical trial?

Hennepin Healthcare Research InstituteLead Sponsor
89 Previous Clinical Trials
76,389 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are octogenarians being considered as participants in this experimentation?

"This clinical trial mandates that participants are between 16 and 55 years of age. Elsewhere, 155 trials open to applicants under the legal age of consent exist while 358 studies accept individuals above 65 years old."

Answered by AI

How many participants are receiving care for this research effort?

"Yes, indeed. Clinicaltrials.gov's records reveal that this clinical trial began recruitment on January 19th 2018 and was most recently updated on December 5th 2022. 220 volunteers will be accepted across a single location for the experiment."

Answered by AI

What are the eligibility requirements for participating in this clinical research?

"This trial requires 220 volunteers suffering from asthma, aged between 16 and 55. More specifically, enrolment must start 15 minutes after being admitted to the ED and participants need to have a functioning phone number in order for our team to contact them 72 hours post-encounter."

Answered by AI

Are health care professionals currently accepting volunteers for this clinical experiment?

"Data on clinicaltrials.gov reveals that this trial, which has been ongoing since January 19th 2018, is actively seeking candidates. The study was last adjusted on December 5th 2022."

Answered by AI

Who else is applying?

What state do they live in?
Minnesota
What site did they apply to?
Hennepin County Medical Center
What portion of applicants met pre-screening criteria?
Met criteria
~26 spots leftby Mar 2025