Reviewed by Michael Gill, B. Sc.
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Most Recent Latisse Clinical Trials

What Are Latisse Clinical Trials?

Latisse is one of the brand names for a bimatoprost ophthalmic solution, which is the first and only FDA approved eyelash serum. Bimatoprost ophthalmic solution has a dual functionality; cosmetically it can be used to grow and thicken eyelashes, and medically it can be used to treat glaucoma. Latisse in particular is used to treat hypotrichosis (hair loss) of the eyelashes. The purpose of the serum is to increase eyelash growth, thickness, length, and darkness. Prior to approval, clinical studies tested the effectiveness and safety of Latisse on the lashes and surrounding areas.

Why Is Latisse Being Studied In Clinical Trials?

Clinical trials for Latisse generally investigate its effectiveness in regrowing eyelashes, appropriate dosage and duration, and assessment of patient satisfaction with the product. In one particular clinical trial, it was concluded that 107 out of 137 participants (or 78%) saw a dramatic increase in the prominence of their eyelashes. All saw their lashes grow to varying degrees with 25% reporting a dramatic increase in length, and 18% reporting a dramatic increase in pigment (color).

On a small scale, Latisse may cause irritation to the surface of the eyeball and eyelid. It was also found that participants had differences in the length, thickness, and direction of growth.

Discontinued use of Latisse will return lashes to their pretreatment condition. Some trials also investigate the effectiveness of Latisse on eyebrows. Participants who were experiencing thinning of the eyebrows placed one drop on each brow daily for 10 months. The results revealed that all participants saw increased eyebrow prominence.

How Does Latisse Treatment Work?

When used to treat glaucoma, bimatoprost ophthalmic solution is applied directly to the eyes via an eye dropper to relieve pressure in the eye. Cosmetically, Latisse functions to increase the length of the growth phase for the eyelashes as well as create more hair follicles.

If you feel you would benefit from Latisse, consult a dermatologist or plastic surgeon. They can prescribe it to you and oversee its use. Fairly simple to use, Latisse is applied once daily (at night), with an applicator. You move the applicator across the base of the upper eyelash. Clinical trials revealed that it is not advisable to use Latisse on the lower lashes because excessive hair growth may occur in that area. In fact, the FDA has only approved Latisse for use on the upper lashes.

What Are Some Breakthrough Clinical Trials Involving Latisse?

2009: A clinical trial was conducted to assess the safety and efficacy of Latisse. It was found that it can irritate the surface of the eyeball.

2016: A clinical trial was conducted that found Latisse, in addition to regrowing eyelashes, can be effective on eyebrows.

2017: A study was conducted on adult subjects suffering from eyelash hypotrichosis due to alopecia. It was found that Latisse was over 70% effective and safe in subjects with this condition.

Who Are Key Opinion Leaders On Latisse Clinical Research?

Kenneth Steinsapir, M.D. is affiliated with the Orbital and Ophthalmic division of Stein Eye Institute and the David Geffen School of Medicine at UCLA. He has researched safety information related to Latisse and has investigated previous clinical trials to assess their validity.

Etty Bitton is a researcher and fellow of the American Academy of Optometry and a professor at the University of Montreal. She has done extensive research trials on how Latisse affects the ocular surface.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 4th, 2021

Last Reviewed: October 18th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References1 Rolim-de-Moura CR, Paranhos A Jr, Loutfi M, Burton D, Wormald R, Evans JR. Laser trabeculoplasty for open-angle glaucoma and ocular hypertension. Cochrane Database Syst Rev. 2022 Aug 9;8:CD003919. doi: 10.1002/14651858.CD003919.pub3. Review. https://pubmed.ncbi.nlm.nih.gov/359431142 Hall LB et al. The Effect of Topical Prostaglandins on Migraine Headaches. Poster Presentation at the Association for Research in Vision and Ophthalmology Annual Meeting, May 2017.