Lymphovenous Bypass Procedure for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial studies whether a surgical procedure called lymphovenous bypass can prevent arm swelling in patients with certain types of breast cancer or melanoma. The surgery creates a new path for fluid to move away from the arms, which may help stop swelling before it starts. Lymphovenous bypass is a surgical procedure that has been used to treat lymphedema by creating a new pathway for lymphatic fluid to drain, potentially reducing swelling.
Will I have to stop taking my current medications?
The trial requires that you stop taking anticoagulants (blood thinners) at least 7 days before the surgery.
How is the Lymphovenous Bypass treatment different from other treatments for breast cancer-related lymphedema?
Lymphovenous Bypass (LVA) is a unique microsurgical procedure that connects tiny lymphatic vessels to small veins, helping to reduce lymphedema (swelling due to lymph fluid buildup) by improving lymphatic drainage. Unlike other treatments, it uses advanced techniques like dynamic ultrasonography to enhance the effectiveness of the procedure by identifying the best vessels for connection.12345
Who Is on the Research Team?
Mark Schaverien
Principal Investigator
M.D. Anderson Cancer Center
Are You a Good Fit for This Trial?
This trial is for adults over 18 with inflammatory or locally advanced non-inflammatory breast cancer, planning to have underarm lymph node surgery and radiation therapy. It's not for pregnant individuals, those unable to follow up for at least 18 months, patients on anticoagulants within a week of surgery, or with a BMI over 50.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Patients receive indocyanine green IV and undergo lymphangiography, then undergo LVB at the time of ALND
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Lymphovenous Bypass
Lymphovenous Bypass is already approved in United States, European Union, Canada, Japan for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator