108 Participants Needed

Parent-Based Treatment for Teenage Anxiety

RE
AM
Overseen ByAlison Magnotti, MA
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Yale University
Must be taking: Stimulants, SSRIs
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests two parent-focused treatments designed to help teenagers with anxiety disorders. One group of parents will learn about Supportive Parenting for Anxious Childhood Emotions (SPACE), while the other will receive Parent Education and Support (PES). Both treatments involve sessions with parents to help manage their teen's anxiety. The trial seeks teens diagnosed with anxiety disorders such as social anxiety or panic disorder who are not taking certain medications or undergoing other treatments. Parents must live with the teen and be willing to participate in the sessions. As an unphased trial, this study offers families a unique opportunity to explore innovative approaches to managing teen anxiety.

Do I need to stop taking my current medications to join the trial?

You don't need to stop taking your current medications if you are on a stable dose of a stimulant or SSRI (a type of antidepressant) for at least 6 months. However, you cannot start any new psychotropic medications during the study.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that the treatment called SPACE (Supportive Parenting for Anxious Childhood Emotions) is easy for parents to use and generally helpful. Studies have shown that SPACE reduces the extent to which parents alter their behavior to accommodate their children's anxiety, indicating it is safe for families.

PES (Parent Education and Support) is another approach that teaches parents how to manage their child's anxiety. Although specific safety data on PES is limited, it is similar to SPACE in focusing on educating and supporting parents. Generally, these programs are considered safe because they help parents rather than directly treating children.

Both SPACE and PES aim to support parents, which in turn benefits their children. Since these treatments do not involve medications or medical procedures, they carry fewer risks.12345

Why are researchers excited about this trial?

Researchers are excited about these treatments for teenage anxiety because they uniquely involve parents as the central focus of intervention. The Supportive Parenting for Anxious Childhood Emotions (SPACE) program is distinctive because it empowers parents to modify their responses to their child's anxiety, rather than directly involving the adolescent in therapy. This contrasts with traditional options like cognitive-behavioral therapy (CBT) or medication, which usually focus on the teenager managing their own anxiety. Meanwhile, the Parent Education and Support (PES) arm serves as a comparator, offering a more conventional parent-based approach, yet still sets itself apart by directly supporting parents over 12 sessions. This trial could pave the way for new, family-centered strategies in managing teenage anxiety.

What evidence suggests that this trial's treatments could be effective for teenage anxiety?

This trial will compare two parent-based treatments for teenage anxiety: Supportive Parenting for Anxious Childhood Emotions (SPACE) and Parent Education and Support (PES). Research has shown that the SPACE program, which involves only parents, effectively reduces family accommodation (when families change their behavior to ease the child's anxiety) and parenting stress. By focusing on these areas, SPACE can help reduce anxiety in teenagers. In contrast, general parent support like PES is important but tends to be less effective in reducing stress reactions in teenagers compared to younger children. Comprehensive studies reviewing multiple research findings suggest that focused parent interventions can be helpful, but their effectiveness can vary. Overall, SPACE seems promising in addressing teenage anxiety by involving parents in a structured way.13678

Who Is on the Research Team?

RE

Rebecca Etkin, PhD

Principal Investigator

Yale University

Are You a Good Fit for This Trial?

This trial is for parents of teenagers who are dealing with anxiety. To participate, the family must be willing to engage in a parent-only treatment approach and commit to assessments throughout the study.

Inclusion Criteria

Have an eligible and willing participating parent
I've been on a stable dose of stimulant or SSRI medication for over 6 months.
I have been diagnosed with an anxiety disorder as per DSM-5.
See 1 more

Exclusion Criteria

Adolescent: Meet criteria for any DSM-5 disorder more impairing than the most impairing anxiety disorder determined by the ADIS-C/P
Adolescent: Have autism spectrum disorder, intellectual disability, neurocognitive disorders, bipolar disorder, schizophrenia, other psychotic disorders, alcohol, or substance use disorders determined by the Health History Form and ADIS-C/P
Adolescent: Report a suicide attempt in the last 3 months or current suicide intent and plans determined by the ASQ
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either SPACE or PES treatment over 12 sessions

12 weeks
12 sessions (in-person or via Zoom)

Mid-treatment assessment

Assessment of progress and adjustment of treatment if necessary

1 week
1 assessment (in-person or virtual)

Post-treatment assessment

Final assessment to evaluate treatment outcomes

1 week
1 assessment (in-person or virtual)

Follow-up

Participants are monitored for safety and effectiveness after treatment

2 weeks
1 follow-up assessment (in-person or virtual)

What Are the Treatments Tested in This Trial?

Interventions

  • Parent Educational Support (PES)
  • Supportive Parenting for Anxious Childhood Emotions (SPACE)
Trial Overview The trial is testing two different parent-based treatments for teenage anxiety: SPACE (Supportive Parenting for Anxious Childhood Emotions) versus PES (Parent Educational Support). It's a randomized controlled trial with participants split into two groups by chance.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Supportive Parenting for Anxious Childhood Emotions (SPACE)Experimental Treatment1 Intervention
Group II: Parent Education and Support (PES)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Yale University

Lead Sponsor

Trials
1,963
Recruited
3,046,000+

MQ: Transforming Mental Health

Collaborator

Citations

Parent-Based Treatment for Adolescent AnxietyThis study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for ...
Parental Involvement in Adolescent Psychological ...Parent support is less effective in buffering cortisol stress reactivity for adolescents compared to children. Developmental Science, 18(2) ...
Supporting parents to reduce children's anxiety: A meta ...The present meta-analysis estimates the effects of parent-focused interventions on child anxiety and aims to identify the most effective intervention content ( ...
Exploring Family Functioning and Adolescent Academic AnxietyThis study highlights the important role of family functioning in reducing academic anxiety among adolescents, mediated by emotional stability and social ...
Benchmarked effectiveness of family and school ...This meta-analysis presented 15 studies on CBT for adolescent anxiety, with 4 studies with adolescents receiving treatment in routine clinical care. The ...
Parent-Based Treatment for Adolescent AnxietyThis study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for ...
A Systematic Review of Parental Involvement in Cognitive ...This systematic review evaluated how parents have been involved and associated treatment outcomes in studies of CBT for adolescent anxiety disorders.
Data and Statistics on Children's Mental HealthThis page provides data about indicators of positive mental health in children and mental health conditions that are most common in children.
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