Study Summary
This trial is studying how well estradiol works in treating patients with a certain type of breast cancer that has spread.
- Triple Negative Breast Cancer
- Breast Cancer
- Stage III Breast Cancer
- Stage IV Breast Cancer
- Stage IIIA Breast Cancer
- Stage IIIB Breast Cancer
- Metastatic Triple-Negative Breast Cancer
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 5 Secondary · Reporting Duration: 5 years
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
1 Treatment Group
Treatment (estradiol)
1 of 1
Experimental Treatment
38 Total Participants · 1 Treatment Group
Primary Treatment: Therapeutic Estradiol · No Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · Female Participants · 0 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Are there long-term risks associated with taking Therapeutic Estradiol?
"Power's team has rated the safety of Therapeutic Estradiol as a 2. This is due to it being in Phase 2 clinical trials, where there is evidence of safety but not yet efficacy." - Anonymous Online Contributor
Are participants being recruited for this clinical research at present?
"That is correct.if you visit clinicaltrials.gov, you'll see that the most recent update to this study was on 8/31/2022. The trial is seeking 38 individuals who are willing to participate at 14 different locations." - Anonymous Online Contributor
In how many different geographical areas is this trial taking place?
"Presently, this trial is being conducted in 14 different centres. These locations include Jacksonville, Chicago and Bronx as well other surrounding areas. If you are interested in enrolling, it would be beneficial to choose the site closest to your residence to cut down on commute times." - Anonymous Online Contributor
How many people are helping to test this new medication?
"Yes, the data on clinicaltrials.gov indicates that this study is looking for participants. The trial was first posted on 8/28/2019 and was last updated on 8/31/2022. 38 patients need to be recruited from 14 different sites." - Anonymous Online Contributor
Do you know of any other times when Therapeutic Estradiol has been studied?
"Estradiol's therapeutic effects were first investigated in 1996 at the National Institutes of Health Clinical Center. To date, there have been a total of 351 completed trials worldwide. There are currently 52 live clinical trials, with a significant portion taking place in Jacksonville, Florida." - Anonymous Online Contributor
What are the benefits of taking Therapeutic Estradiol?
"Therapeutic Estradiol is most commonly used to treat amenorrhea, or the absence of a menstrual period, in women who have not had one in the last 6 months. However, it can also be helpful for managing other conditions like hypoestrogenism, menopausal vasomotor symptoms, and breast cancer." - Anonymous Online Contributor