Travoprost Implant for Glaucoma
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a small device that releases medication inside the eye to help patients with high eye pressure due to glaucoma or ocular hypertension. The medication helps fluid drain from the eye, reducing pressure and preventing vision problems.
Do I need to stop my current medications for the trial?
Yes, you will need to stop taking your current glaucoma medications as part of the study requirements, but only if the investigator believes it can be done safely.
Is the Travoprost Implant for Glaucoma safe for humans?
How is the Travoprost Implant for Glaucoma different from other glaucoma treatments?
What data supports the effectiveness of this drug for glaucoma?
The bimatoprost implant (Durysta) has been shown to effectively lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension, as demonstrated in studies where it reduced IOP over a 4- to 6-month period. Additionally, a retrospective study found that most patients experienced a reduction in IOP after receiving the implant.12345
Are You a Good Fit for This Trial?
This trial is for adults with Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT). Participants must be willing to stop their glaucoma medications as per study rules and not be at risk by doing so. Pregnant or breastfeeding individuals, those unresponsive to certain eye pressure-lowering drugs, or with uncontrolled diseases like severe diabetes are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single sustained release dose of the OTX-TIC drug product (2 travoprost dose strengths) or a single injection of DurystaTM
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Durysta, Bimatoprost Intracameral Implant 10 µg
- OTX-TIC high dose Travoprost Intracameral Implant
- OTX-TIC low dose Travoprost Intracameral Implant
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ocular Therapeutix, Inc.
Lead Sponsor