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Prostaglandin Analog
Group 2: Normal tension glaucoma subjects with thick corneas for Normal Tension Glaucoma (NTG Trial)
Phase 4
Waitlist Available
Research Sponsored by Salus University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months post-treatment
Awards & highlights
NTG Trial Summary
This study is evaluating whether a drug called netarsudil can be used to treat glaucoma in people with thicker corneas and higher levels of corneal hysteresis.
Eligible Conditions
- Normal Tension Glaucoma
NTG Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 3 months post-treatment
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months post-treatment
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Post-treatment IOP
Secondary outcome measures
Post-treatment IOP change by CCT
Post-treatment IOP change by CH
Post-treatment change in CCT
+1 moreNTG Trial Design
2Treatment groups
Experimental Treatment
Group I: Group 2: Normal tension glaucoma subjects with thick corneasExperimental Treatment2 Interventions
NTG subjects with CCT > 540 nm will be randomized to receive either netarsudil or bimatoprost.
Group II: Group 1: Normal tension glaucoma subjects with thin corneasExperimental Treatment2 Interventions
NTG subjects with CCT ≤ 540 nm will be randomized to receive either netarsudil or bimatoprost.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Netarsudil
FDA approved
Bimatoprost
FDA approved
Find a Location
Who is running the clinical trial?
Salus UniversityLead Sponsor
14 Previous Clinical Trials
842 Total Patients Enrolled
Jingyun Wang, Ph.DStudy DirectorSalus University
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