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Nonsteroidal Anti-inflammatory Drug

Ketorolac Dosing for Acute Pain

Phase 4

Waitlist Available

Led By Matthew Robinson, MD

Research Sponsored by University of Missouri-Columbia

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

> 18 y/o

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 30 minutes

Awards & highlights

Study Summary

This trial will compare three different doses of ketorolac to find the best one for treating pain in the emergency department.

Who is the study for?

This trial is for adults over 18 who come to the Emergency Department with acute pain. It's not suitable for pregnant individuals, those allergic to ketorolac, or anyone with a condition that would make taking the drug unsafe.Check my eligibility

What is being tested?

The study aims to find out the best dose of ketorolac for treating pain in an emergency setting by comparing three different doses and seeing which one works best without causing too many side effects.See study design

What are the potential side effects?

Ketorolac can cause stomach upset, bleeding, kidney problems, dizziness, and headaches. The risk of side effects may increase with higher doses.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am over 18 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 30 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~30 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Intensity of pain

Trial Design

3Treatment groups

Active Control

Placebo Group

Group I: 30 mgActive Control1 Intervention

30 mg ketorolac - usual dose ketorolac

Group II: 10 mgActive Control1 Intervention

10 mg ketorolac - low dose ketorolac

Group III: 0 mgPlacebo Group1 Intervention

0 mg ketorolac - placebo

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Missouri-ColumbiaLead Sponsor

361 Previous Clinical Trials

627,494 Total Patients Enrolled

1 Trials studying Acute Pain

10 Patients Enrolled for Acute Pain

Matthew Robinson, MDPrincipal Investigator - University of Missouri-Columbia

Curators of the University of Missouri, Ellis Fischel Cancer Center of University of Missouri, University of Missouri Hospital

University Of Mo (Medical School)

Naval Reg Medical Center (Residency)

Media Library

Ketorolac (Nonsteroidal Anti-inflammatory Drug) Clinical Trial Eligibility Overview. Trial Name: NCT03464461 — Phase 4

Acute Pain Research Study Groups: 30 mg, 10 mg, 0 mg

Acute Pain Clinical Trial 2023: Ketorolac Highlights & Side Effects. Trial Name: NCT03464461 — Phase 4

Ketorolac (Nonsteroidal Anti-inflammatory Drug) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03464461 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What other experiments have been conducted with a 10 mg dose?

"Presently, 38 studies are being conducted for 10 mg. Of those trials, 8 have reached Phase 3 status. Most of these tests are based in Los Angeles but a total of 57 clinical centres all over the country are participating."

Answered by AI

Could you elucidate the potential risks to patients of a 10 mg dosage?

"Our organisation has determined that a 10 mg dose of this medication is safe and secure, granting it the maximum score of 3 on our rating system. This level indicates that the drug already holds approval from regulatory bodies."

Answered by AI

How many subjects are participating in this research?

"Affirmative. The data from clinicaltrials.gov indicates that this medical investigation is currently accepting participants, first posted on May 1st 2018 and most recently updated on May 17th 2022. Around 700 individuals will be admitted at a single trial site."

Answered by AI

Is the opportunity to join this research endeavor still available to volunteers?

"Per the information on clinicaltrials.gov, this research is actively seeking participants. It was first published in May 2018 and revised only recently in May 2022."

Answered by AI

What conditions are usually remedied by a 10 mg dosage?

"Typically, 10 mg of the medication is prescribed in order to relieve ocular itching. It may also be useful for managing pain and triggering nerve blockage or pupil dilation."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Dosing of Ketorolac in the Emergency Department

Matthew Robinson 2018. "Dosing of Ketorolac in the Emergency Department". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03464461.

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