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uEXPLORER vs Conventional PET/CT Imaging for Cancer

N/A

Waitlist Available

Led By Lorenzo Nardo, MD

Research Sponsored by University of California, Davis

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis or suspected diagnosis of lung cancer, melanoma or lymphoma.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up one imaging visit up to two hours

Awards & highlights

Study Summary

This trial will compare the image quality of two types of PET/CT scans to see which one requires the shorter scan duration.

Who is the study for?

This trial is for men and women over 18 who can consent to participate, have or might have lung cancer, lymphoma, or melanoma, and need a PET/CT scan. It's not for pregnant individuals, those with claustrophobia, or anyone with a condition that could affect their safety in the study.Check my eligibility

What is being tested?

The trial is testing if shorter scans using a new total-body PET/CT scanner (uEXPLORER) are as good as longer ones on conventional scanners for patients with lung cancer, lymphoma, or melanoma. Participants will undergo both types of scans.See study design

What are the potential side effects?

Since this trial involves imaging techniques rather than drugs, side effects may include discomfort from lying still during the scan and potential reactions to contrast agents used in imaging.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have or may have lung cancer, melanoma, or lymphoma.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ one imaging visit up to two hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~one imaging visit up to two hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and one imaging visit up to two hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Minimum scan duration on a total-body PET/CT scanner for quality

Secondary outcome measures

Minimum scan duration on a total-body PET/CT scanner for tumor recognition

Trial Design

2Treatment groups

Experimental Treatment

Group I: uEXPLORER/mCTExperimental Treatment1 Intervention

Each patient will undergo a scan on a total-body PET/CT scanner (uEXPLORER) and then undergo an additional scan on a conventional PET/CT scanner (mCT). The first scan will take place 60 minutes after injection with 18F-FDG and the second scan will be 90 minutes after injection with 18F-FDG.

Group II: mCT/uEXPLORERExperimental Treatment1 Intervention

Each patient will undergo a scan on a conventional PET/CT scanner (mCT) and then undergo an additional scan on a total-body PET/CT scanner (uEXPLORER) . The first scan will take place 60 minutes after injection with 18F-FDG and the second scan will be 90 minutes after injection with 18F-FDG.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

uEXPLORER/mCT

2021

N/A

~20

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor

910 Previous Clinical Trials

4,706,811 Total Patients Enrolled

9 Trials studying Lymphoma

585 Patients Enrolled for Lymphoma

Lorenzo Nardo, MDPrincipal InvestigatorUC Davis Department of Radiology

3 Previous Clinical Trials

107 Total Patients Enrolled

Media Library

uEXPLORER/mCT Clinical Trial Eligibility Overview. Trial Name: NCT04478318 — N/A

Lymphoma Research Study Groups: uEXPLORER/mCT, mCT/uEXPLORER

Lymphoma Clinical Trial 2023: uEXPLORER/mCT Highlights & Side Effects. Trial Name: NCT04478318 — N/A

uEXPLORER/mCT 2023 Treatment Timeline for Medical Study. Trial Name: NCT04478318 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research initiative currently looking for individuals to participate?

"According to clinicaltrials.gov, this particular research project is not actively enrolling any more participants; the original posting was on June 1st 2020 and it's last update came on September 29th 2022. Fortunately, there are other 3895 trials that currently require volunteers for their studies."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma

2020. "Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04478318.

All > Melanoma