uEXPLORER vs Conventional PET/CT Imaging for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
To determine the minimum scan duration for fluorine-18 positron-emitting radioactive isotope-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) scans performed on a total-body PET/CT scanner that results in non-inferior image quality to 18F-FDG PET/CT scans performed on a conventional PET/CT scanner. The subject population will be patients being staged for lung cancer, lymphoma, or melanoma.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is uEXPLORER PET/CT imaging safe for humans?
The uEXPLORER PET/CT scanner has been used in clinical settings and provides high-quality imaging with lower radiation doses, which suggests it is generally safe for human use. It offers better image quality and lower noise compared to conventional PET/CT, which can improve the accuracy of medical assessments.12345
How does the uEXPLORER PET/CT treatment differ from conventional PET/CT imaging for cancer?
The uEXPLORER PET/CT treatment is unique because it offers total-body imaging, which provides more comprehensive information about the disease compared to conventional PET/CT. It allows for low-dose or even extra low-dose scanning, reducing radiation exposure while maintaining high-quality imaging, and can dynamically assess tumor characteristics.13678
What data supports the effectiveness of the treatment mCT/uEXPLORER, uEXPLORER/mCT in the clinical trial titled 'uEXPLORER vs Conventional PET/CT Imaging for Cancer'?
Research shows that combining PET with CT in imaging provides better anatomical details and faster imaging, which is particularly useful in cancer care for staging tumors and monitoring therapy. This combined imaging approach has been shown to improve survival in certain cancers, like breast cancer and lung cancer, by helping doctors make more informed treatment decisions.69101112
Who Is on the Research Team?
Lorenzo Nardo, MD
Principal Investigator
UC Davis Department of Radiology
Are You a Good Fit for This Trial?
This trial is for men and women over 18 who can consent to participate, have or might have lung cancer, lymphoma, or melanoma, and need a PET/CT scan. It's not for pregnant individuals, those with claustrophobia, or anyone with a condition that could affect their safety in the study.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging
Participants undergo PET/CT scans on both uEXPLORER and conventional PET/CT scanners to compare image quality and tumor recognition
Follow-up
Participants are monitored for any adverse effects following the imaging procedures
What Are the Treatments Tested in This Trial?
Interventions
- mCT/uEXPLORER
- uEXPLORER/mCT
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Davis
Lead Sponsor