Your session is about to expire
← Back to Search
Simulated Night Shift for Circadian Rhythm Disorder (SPOTLIGHT Trial)
SPOTLIGHT Trial Summary
This trial will study the effects of night shift work on bone metabolism, specifically if it causes bone turnover markers to become uncoupled, and if this is due to increased sympathetic nervous system activity.
SPOTLIGHT Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSPOTLIGHT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.SPOTLIGHT Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- You have smoked within the past year.Your bone density is very low compared to the average for your age and gender.Your vitamin D level is less than 20 ng/mL.I am a premenopausal woman not breastfeeding and on birth control pills.Your physical activity routine doesn't work with staying in the hospital for the study.You have a medical condition that is not well understood or not well managed.You have worked night shifts within the past year before the study.I have not traveled across time zones recently and won't need to during the study.I have been treated with medications for mental health issues but don't know my specific diagnosis.My kidney function is reduced, with an eGFR below 60.I haven't had any major health issues or head injuries in the past year.I understand what is required of me in this study.I am currently taking prescribed anti-depressants or similar medications.I haven't taken drugs affecting sleep or bones in the last month.I do not have symptoms like fever at the time of enrollment.I cannot travel to the CU-AMC campus for study visits.I am a healthy adult, aged 20-40, not pregnant, and I usually sleep 7-9 hours at night.You have a serious mental health condition, as defined by DSM-V.You have lived at an altitude below 1,600 meters (about 1 mile) in Denver for the month before joining the study.People who follow strict diets.You tested positive for drugs during the screening or when admitted to the hospital.I am a healthy adult, aged 20-40, who sleeps 7-9 hours at night and am not pregnant.I have a serious sleep disorder.You have a body mass index (BMI) higher than 30 kg/m2.You regularly go to sleep after 12:00 AM.I am taking medication that affects bone health.You drink a lot of caffeine or alcohol.I am a premenopausal woman not breastfeeding and on birth control pills.
- Group 1: Control (8 hours nocturnal sleep)
- Group 2: Simulated Night Shift Work
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the age range for participation in this medical experiment inclusive of patients older than 70?
"According to the research protocol, only individuals between 20 and 40 years old are eligible for this trial."
Are there currently any enrolment opportunities for this experiment?
"As detailed on clinicaltrials.gov, the study is actively searching for participants to join their trial that was posted on February 8th 2022 and amended most recently November 1st of the same year."
What is the current capacity of this experiment?
"Affirmative. Clinicaltrials.gov hosts records that confirm this trial, which was first publicized on February 8th 2022, is actively enrolling interested parties. As of now, only 20 patients need to be enrolled from one single medical centre."
What are the eligibility criteria for participation in this research?
"The requirements for this medical trial is that candidates should be between 20 and 40 years old, and possess bone resorption. A total of 20 individuals will qualify to take part in the study."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Share this study with friends
Copy Link
Messenger