32 Participants Needed

HIIT Exercise for Endometrial Cancer

LC
AS
Overseen ByAbbie Smith-Ryan, PhD
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: UNC Lineberger Comprehensive Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This interventional trial recruits women with endometrial cancer to participate in high intensity interval training (HIIT) prior to their standard of care surgery. The study will evaluate tissue and blood to determine if HIIT training has anti-cancer effects. P

Who Is on the Research Team?

Victoria L. Bae-Jump - UNC Lineberger

Victoria Bae-Jump, MD, PhD

Principal Investigator

University of North Carolina, Chapel Hill

Are You a Good Fit for This Trial?

Women aged 40-75 with endometrial cancer, scheduled for surgery, and a BMI of 30-50 kg/m2 can join. They must have early-stage disease, access to email and a smartphone, and be able to visit the lab for tests. Those with recent severe cardiovascular events, other interventions or conditions that limit safe participation are excluded.

Inclusion Criteria

Your body mass index (BMI) is between 30 and 50, which means you may be overweight or have obesity.
I agree to visit the lab for baseline testing within 2 days if it can't be done the same day as my standard of care visit.
I have access to email.
See 6 more

Exclusion Criteria

I have severe hearing or speech impairments.
You have a serious mental health condition.
You currently have a mental illness called psychosis or you are dealing with substance abuse problems that are not under control.
See 9 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Testing

Participants undergo baseline testing and are taught how to perform personalized HIIT training

1 week

HIIT Exercise

Participants perform high intensity interval training prior to their standard of care surgery

2-4 weeks

Surgery and Post-Surgery Testing

Participants undergo standard of care surgery and repeat testing

1 week

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • HIIT exercise
Trial Overview The trial studies the effects of high intensity interval training (HIIT) on women with endometrial cancer before their standard surgery. It aims to see if HIIT has anti-cancer benefits by examining changes in tissue and blood markers.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: HIIT exerciseExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

UNC Lineberger Comprehensive Cancer Center

Lead Sponsor

Trials
377
Recruited
95,900+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+
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