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Transcranial Alternating Current Stimulation (tACS) for Alzheimer's Disease
Study Summary
This trial will investigate whether transcranial alternating current stimulation (tACS) can decrease the amount of amyloid and tau in people with Alzheimer's Disease (AD), as compared to Sham (placebo) stimulation.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I frequently take medication to prevent severe headaches.I cannot have MRI scans or undergo TMS or tACS treatments.You have had problems with drugs or alcohol in the past six months.I am at least 45 years old.I have a history of seizures or epilepsy, except for a single benign seizure.My doctor will review my medications to decide if I can join the trial.I have been on a steady dose of memory loss medication for at least 6 weeks.I have a neurological condition other than dementia, or I've had neurosurgery or head trauma with lasting effects.You have a history of severe mental health conditions like depression, bipolar disorder, or psychosis.You have been diagnosed with mild to severe dementia.I have been diagnosed with early to moderate Alzheimer's disease.I have had fainting spells that might be seizures.My brain scan shows changes or small strokes that don't affect my thinking or movement.I don't have chronic conditions like heart issues or asthma that could worsen with a seizure.I am not pregnant or breastfeeding.The study doctor will confirm the diagnosis by considering the participant's cognitive evaluation and personal history.You have problems with your memory or have had memory issues in the past.You do not have a history of intellectual disability.
- Group 1: 4 weeks of daily tACS sessions
- Group 2: 4 weeks of twice daily tACS sessions
- Group 3: 2/4 weeks of Sham tACS sessions
- Group 4: 2 weeks of daily tACS sessions
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many total participants are enrolled in this clinical trial?
"This is an active recruitment according to the information displayed on clinicaltrials.gov. The trial was created on 8/5/2019, and the most recent update was 10/6/2022. Currently, 55 patients are needed for the study that is taking place at 1 site."
Are researchers still enrolling people for this trial?
"That is correct, the listed clinical trial on clinicaltrials.gov is currently recruiting patients. The first posting was on August 5th, 2019 with the latest update being October 6th, 2022. This study will have 55 participants at a single location."
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