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tACS + Cognitive Exercises for Dementia (tACS Trial)

N/A

Recruiting

Research Sponsored by University of Manitoba

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline (week 0), week 5, week 11, week 16

Awards & highlights

tACS Trial Summary

This trial is investigating the effect of tACS, a brain stimulation technique, on cognitive ability. Participants will be randomized to receive either active tACS or sham tACS for 4 weeks, then 8 weeks without any treatment, followed by another 4 weeks of the opposite treatment. The study is double-blind, meaning neither the participants nor the assessors will know which group the participants are in.

Who is the study for?

This trial is for English-speaking individuals with dementia or mild cognitive impairment. It's not suitable for those with Parkinson's, major mood disorders, epilepsy, severe vision/hearing issues, substance abuse disorder, or those in another dementia study. Participants shouldn't plan to change medications during the study.Check my eligibility

What is being tested?

The trial tests transcranial alternative current stimulation (tACS) combined with cognitive exercises using an app. Participants are split into two groups; one starts with active tACS and ends with sham treatment after a break period while the other group does the opposite sequence.See study design

What are the potential side effects?

Potential side effects of tACS may include discomfort at electrode sites, headache, fatigue or dizziness post-treatment. Cognitive exercises might cause mental fatigue but generally have minimal risks.

tACS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline (week 0), week 5, week 11, week 16

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline (week 0), week 5, week 11, week 16

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (week 0), week 5, week 11, week 16 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change from baseline Wechsler Memory Scale (WMS-IV) Older Adult Battery Score at five, eleven and sixteen weeks.

Secondary outcome measures

Electrovestibulography (EVestG)

Functional Near Infrared Spectroscopy (fNIRS)

N-back test

+3 more

tACS Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Group 1 (G1)Experimental Treatment2 Interventions

Participants will receive active tACS simultaneously with cognitive exercises.

Group II: Group 2 (G2)Placebo Group1 Intervention

Participants will receive sham tACS simultaneously with cognitive exercises.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of ManitobaLead Sponsor

595 Previous Clinical Trials

199,422 Total Patients Enrolled

Riverview Health Centre FoundationOTHER

5 Previous Clinical Trials

265 Total Patients Enrolled

Charis Senior Residences LP. DBA Aster GardensUNKNOWN

Media Library

Cognitive Exercises 2023 Treatment Timeline for Medical Study. Trial Name: NCT05203523 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age restriction for this clinical trial strictly limited to adults over 25?

"As outlined in the study's criteria, participants must fall within a certain age range of 50 to 95 years old."

Answered by AI

How many participants are currently being admitted to this medical trial?

"Exactly, clinicaltrials.gov's records verify that this investigation is currently seeking volunteers; the trial was first published on January 24th 2022 and updated most recently February 14th 2022. This study requires 100 particpants from 2 different medical centres to take part in it."

Answered by AI

Is it possible for me to volunteer as a participant in this clinical experiment?

"To enroll in this medical experiment, participants must possess mild dementia and be aged between 50 to 95 years old. Approximately 100 volunteers are sought after for the trial."

Answered by AI

Is enrollment for this research trial still available?

"Affirmative, the information present on clinicaltrials.gov signals that this investigation is actively looking for participants. This research was first listed on 1/24/2022 and subsequently updated to its current version on 2/14/2022. A total of 100 patients are required between two sites."

Answered by AI

Recent research and studies

JMIR Research ProtocolsJournal

The Effect of Transcranial Alternating Current Stimulation with Cognitive Training on Executive Brain Function in Individuals with Dementia: Protocol for a Crossover Randomized Controlled Trial

Jacobson, Natasha, Brian Lithgow, Mohammad Jafari Jozani, and Zahra Moussavi. 2022. “The Effect of Transcranial Alternating Current Stimulation with Cognitive Training on Executive Brain Function in Individuals with Dementia: Protocol for a Crossover Randomized Controlled Trial”. JMIR Research Protocols. JMIR Publications Inc.. doi:10.2196/37282.

clinicaltrials.govStudy

Investigational Dementia Treatment Study

Dr. Zahra Kazem-Moussavi 2022. "Investigational Dementia Treatment Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05203523.