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Behavioural Intervention

Cognitive Training for Healthy Older Adults (SPECTRA Trial)

N/A

Recruiting

Led By Sylvie Belleville, PhD

Research Sponsored by Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

French-speaking

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up in the week preceding the start of the intervention (pre); in the week of the last intervention session (post)

Awards & highlights

SPECTRA Trial Summary

This trial looks at how cognitive training can improve memory and quality of life in seniors by studying brain changes before and after training.

Who is the study for?

This trial is for healthy, French-speaking, right-handed older adults with good vision and hearing. They must have a certain level of memory ability based on their education. People can't join if they've had recent major surgery or anesthesia, low cognitive scores, brain diseases or injuries, severe psychiatric conditions, substance abuse issues, or are unable to undergo an MRI.Check my eligibility

What is being tested?

The study tests whether a specific type of memory training (Episodic Specificity Induction) improves episodic retrieval in aging individuals compared to standard word-image recall exercises. It measures changes in behavior and brain function before and after the training using tasks and MRI scans.See study design

What are the potential side effects?

There are no direct side effects from the interventions being studied as they involve non-invasive cognitive training techniques. However, participants may experience discomfort from sitting still during MRI scans.

SPECTRA Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

SPECTRA Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ in the week preceding the start of the intervention (pre); in the week of the last intervention session (post)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~in the week preceding the start of the intervention (pre); in the week of the last intervention session (post)

This trial's timeline: 3 weeks for screening, Varies for treatment, and in the week preceding the start of the intervention (pre); in the week of the last intervention session (post) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in the number of correct specific detail recall (nearest transfer outcome)

Secondary outcome measures

Brain function: Memory related activation

Brain function: Memory related activation (Dynamic functional connectivity)

Brain function: Memory related activation (Static functional connectivity)

+3 more

Other outcome measures

Effect of moderators: Cognitive reserve proxies.

Effect of moderators: Sex.

SPECTRA Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Episodic Specificity InductionExperimental Treatment1 Intervention

In each of the six training sessions, participants practice the ESI first under supervision and then unsupervised (self-administered). Self-administration is performed on a laptop. During each practice of the ESI, participants perform a detailed recall of a new 1-minute video clip of a complex scene - a skit of the famous English comedian Mr. Bean. Each session lasts for 90 minutes.

Group II: Associative MemoryActive Control1 Intervention

In each of the six training sessions, participants recall pairs of words and pictures (e.g., names of women and rings). These pairs are presented successively after a fictitious scenario is presented to motivate memorization. There are 12 scenarios, each with 5 different word/picture pairs. Simple additions and subtractions separate the encoding phase from the recall phase. This training is adapted from Bellander et al, (2017). A general knowledge quiz is also administered at the end of the session. The training is performed on a laptop. Each session lasts for 90 minutes.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Centre de Recherche de l'Institut Universitaire de Geriatrie de MontrealLead Sponsor

22 Previous Clinical Trials

8,829 Total Patients Enrolled

Canadian Institutes of Health Research (CIHR)OTHER_GOV

1,341 Previous Clinical Trials

26,452,653 Total Patients Enrolled

Natural Sciences and Engineering Research Council, CanadaOTHER

57 Previous Clinical Trials

3,029 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this medical experiment offer enrolment for individuals aged 30 or older?

"Specific criteria for this clinical trial requires potential participants to be between 60 and 85 years of age."

Answered by AI

How many individuals are partaking in this research experiment?

"Affirmative. Clinicaltrials.gov displays that this experiment is presently seeking out participants, having been first uploaded on September 22nd 2023 and subsequently amended on October 26th 2023. Sixty subjects are needed at a single location."

Answered by AI

What are the eligibility requirements to take part in this experiment?

"For inclusion in this clinical trial, participants should be between 60 and 85 years old with no health complications. Currently, there is room for roughly 60 individuals to join the study."

Answered by AI

Are there any opportunities to participate in this trial right now?

"Affirmative. According to the information available on clinicaltrials.gov, this medical trial is still actively recruiting participants and was first posted on September 22nd 2023 and last updated a month later. The research team requires 60 individuals from one particular site for their study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults.

Sylvie Belleville 2023. "Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06110234.