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Working Memory Training for Cognitive Impairment in Older Adults

N/A

Recruiting

Led By Aaron R Seitz, Phd

Research Sponsored by University of California, Irvine

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 25, day 47, day 79

Awards & highlights

Study Summary

This trial will help to determine how different types of working memory training programs can be tailored to optimize outcomes in older adults.

Who is the study for?

This trial is for older adults aged 50-85 who speak English and can follow the study's procedures. They must not have psychological or neurological conditions that affect consent, be involved in other memory studies, or have certain cognitive impairments as measured by specific tests.Check my eligibility

What is being tested?

The study examines how different working memory training methods affect older adults. It uses a randomized crossover design to test gamified vs non-gamified tasks and multisensory vs visual-only information to see which improves learning based on individual cognitive abilities.See study design

What are the potential side effects?

Since this is a non-medical intervention focusing on working memory training, typical medical side effects are not expected. However, participants may experience mental fatigue or frustration during challenging cognitive tasks.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 25, day 47, day 79

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 25, day 47, day 79

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 25, day 47, day 79 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Corsi span

Change in Everyday Memory Questionnaire Revised

Change in Inhibitory Control Composite Score

+1 more

Secondary outcome measures

Exit Survey

Training Experience Difficulty Subscale I

Training Experience Difficulty Subscale II

+6 more

Other outcome measures

Change in General Cognitive Ability Composite Score

Trial Design

2Treatment groups

Active Control

Group I: Condition 1Active Control3 Interventions

Training type 1 will be administered in the first part of the crossover trial and Training type 2 will be administered in the second part of the trial. Each training part consists of 20 twenty-minute long sessions with the recommended frequency of 2 sessions per work day. Thus each training part can be completed in 10 work days (2 weeks).

Group II: Condition 2Active Control3 Interventions

Training type 2 will be administered in the first part of the crossover trial and Training type 1 will be administered in the second part of the trial. Each training part consists of 20 twenty-minute long sessions with the recommended frequency of 2 sessions per work day. Thus each training part can be completed in 10 work days (2 weeks).

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of California, RiversideOTHER

24 Previous Clinical Trials

12,016 Total Patients Enrolled

National Institute on Aging (NIA)NIH

1,671 Previous Clinical Trials

28,016,823 Total Patients Enrolled

University of California, IrvineLead Sponsor

543 Previous Clinical Trials

1,922,761 Total Patients Enrolled

Media Library

Multisensory Clinical Trial Eligibility Overview. Trial Name: NCT05396586 — N/A

Cognitive Impairment Research Study Groups: Condition 1, Condition 2

Cognitive Impairment Clinical Trial 2023: Multisensory Highlights & Side Effects. Trial Name: NCT05396586 — N/A

Multisensory 2023 Treatment Timeline for Medical Study. Trial Name: NCT05396586 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the objectives of this experimental research?

"This clinical trial, to be assessed across a 3-point temporal scale (Day 24, Day 46 and Day 78), has the primary aim of measuring Change in Corsi span. Secondary endpoints encompass Training Experience Difficulty Subscale I (1-3 indicating too easy; 4-7 appropriate difficulty; 8-10 too hard); Training Experience Subjective Progress Subscale II (scores range from 1 to 5 with higher scores reflecting greater progress on task) and Training Experience Enjoyment Subscale II (scores also ranging from 1 to 5 but representing enjoyment levels)."

Answered by AI

How can I register to participate in this trial?

"Applicants must meet the age criteria of 50-85 and demonstrate cognitive changes to be eligible for this trial, which is scheduled to recruit a total of 240 individuals."

Answered by AI

Does this trial cater to individuals aged fifty-five and under?

"In congruence with the prerequisites for this trial, participants must be aged 50 and above but not surpassing 85 years old."

Answered by AI

How many participants are currently taking part in this clinical research?

"Affirmative. Information found on clinicaltrials.gov indicates that this medical research is actively enrolling individuals, with the initial posting being made on March 30th 2022 and most recently updated May 24th of the same year. The study requires a total of 240 patients to be recruited from two different sites."

Answered by AI

Are there openings available for enrollment in this research trial?

"Affirmative. Clinicaltrials.gov attests that as of May 24th, 2022 this research is actively recruiting patients; 240 individuals need to be identified from two distinct clinical sites since the study's posting on March 30th, 2022."

Answered by AI

Recent research and studies

Disability and RehabilitationJournal

The Everyday Memory Questionnaire – Revised: Development of a 13-item Scale

Royle, Jane, and Nadina B. Lincoln. 2008. “The Everyday Memory Questionnaire – Revised: Development of a 13-item Scale”. Disability and Rehabilitation. Informa UK Limited. doi:10.1080/09638280701223876.

Journal of Cognitive EnhancementJournal

Multisensory Facilitation of Working Memory Training

Pahor, Anja, Cindy Collins, Rachel N. Smith-Peirce, Austin Moon, Trevor Stavropoulos, Ilse Silva, Elaine Peng, Susanne M. Jaeggi, and Aaron R. Seitz. 2020. “Multisensory Facilitation of Working Memory Training”. Journal of Cognitive Enhancement. Springer Science and Business Media LLC. doi:10.1007/s41465-020-00196-y.

Frontiers in PsychologyJournal

Application of Machine Learning Models for Tracking Participant Skills in Cognitive Training

Sandeep, Sanjana, Christian R. Shelton, Anja Pahor, Susanne M. Jaeggi, and Aaron R. Seitz. 2020. “Application of Machine Learning Models for Tracking Participant Skills in Cognitive Training”. Frontiers in Psychology. Frontiers Media SA. doi:10.3389/fpsyg.2020.01532.

Behavior Research MethodsJournal