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Behavioral Activation for Depression

Phase 2

Recruiting

Led By Rebecca Saracino, PhD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 months post intervention

Awards & highlights

Study Summary

This trial tests if psychotherapy delivered by phone/video can help treat depression in older cancer survivors.

Who is the study for?

This trial is for older adults (65+) who have survived cancer, are experiencing mild to moderate depression, and can communicate via phone or video. They must be fluent in English and not require a higher level of psychiatric care. Those with major untreated psychotic disorders or recent changes in antidepressant medication use are excluded.Check my eligibility

What is being tested?

The study tests if behavioral activation therapy, delivered remotely through telephone or videoconference, helps reduce depression in older adult cancer survivors compared to supportive psychotherapy.See study design

What are the potential side effects?

Since the interventions involve psychological therapies rather than medications, side effects may include emotional discomfort during sessions but typically do not involve physical side effects.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 months post intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 months post intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 months post intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Difference of Patient Health Questionnaire 9 (PHQ-9) scores between study groups

Trial Design

2Treatment groups

Experimental Treatment

Group I: Older Adult Cancer Survivors (OACS) - Supportive Psychotherapy (SP)Experimental Treatment1 Intervention

Older adult cancer survivors (OACS) will receive a Supportive Psychotherapy intervention

Group II: Older Adult Cancer Survivors (OACS) - Behavioral Activation (BA)Experimental Treatment1 Intervention

Older adult cancer survivors (OACS) will receive a Behavioral Activation intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Behavioral Activation

2013

Completed Phase 3

~2980

Supportive Psychotherapy

2008

Completed Phase 2

~1210

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor

1,936 Previous Clinical Trials

588,823 Total Patients Enrolled

Rebecca Saracino, PhDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

Media Library

Behavioral Activation Clinical Trial Eligibility Overview. Trial Name: NCT05574127 — Phase 2

Survivorship Research Study Groups: Older Adult Cancer Survivors (OACS) - Supportive Psychotherapy (SP), Older Adult Cancer Survivors (OACS) - Behavioral Activation (BA)

Survivorship Clinical Trial 2023: Behavioral Activation Highlights & Side Effects. Trial Name: NCT05574127 — Phase 2

Behavioral Activation 2023 Treatment Timeline for Medical Study. Trial Name: NCT05574127 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies for the current clinical trial?

"The clinical trial is presently in search of volunteers, which was first posted on October 6th 2022 and has since been amended on February 15th 2023."

Answered by AI

Has the Older Adult Cancer Survivors (OACS) - Behavioral Activation (BA) protocol gained FDA endorsement?

"The safety of Older Adult Cancer Survivors (OACS) - Behavioral Activation (BA) was assessed to be a 2 on the 1-3 scale due to it currently being in its second phase. This suggests that while there is evidence of some level of safety, efficacy has yet to be confirmed."

Answered by AI

How many subjects are actively participating in this clinical experiment?

"Affirmative. According to information on clinicaltrials.gov, this medical investigation is actively recruiting candidates. Originally posted on October 6th 2022 and revised as recently as February 15th 2023, the trial looks for 66 patients at 1 site in particular."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors

2022. "A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05574127.

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