Bilateral TMS for Autism Spectrum Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Autism Spectrum Disorder+7 More
Bilateral TMS - Procedure
Eligibility
< 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial will study whether theta burst stimulation can help ease depression in people with autism spectrum conditions.

Eligible Conditions
  • Autism Spectrum Disorder
  • Autism Spectrum Disorders
  • Major Depressive Disorder (MDD)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Autism Spectrum Disorder

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 4 weeks post-treatment

4 weeks post-treatment
Change-from-baseline at 4 weeks in handgrip strength or relative handgrip strength.
Change-from-baseline at 4 weeks in mean Hamilton Depression Rating Scale (HDRS-17) score.
Change-from-baseline at 4 weeks in mean and Beck Depression Inventory (BDI-II) scores.
Change-from-baseline at 4 weeks in physiological markers via the use of high-resolution electroencephalography (EEG).

Trial Safety

Safety Progress

1 of 3

Other trials for Autism Spectrum Disorder

Trial Design

2 Treatment Groups

Unilateral
1 of 2
Bilateral
1 of 2
Active Control
Experimental Treatment

24 Total Participants · 2 Treatment Groups

Primary Treatment: Bilateral TMS · No Placebo Group · N/A

Bilateral
Procedure
Experimental Group · 1 Intervention: Bilateral TMS · Intervention Types: Procedure
Unilateral
Procedure
ActiveComparator Group · 1 Intervention: Unilateral TMS · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 4 weeks post-treatment

Who is running the clinical trial?

Children's Hospital Medical Center, CincinnatiLead Sponsor
747 Previous Clinical Trials
5,417,494 Total Patients Enrolled
18 Trials studying Autism Spectrum Disorder
9,135 Patients Enrolled for Autism Spectrum Disorder
Ernest Pedapati, MDPrincipal InvestigatorChildren's Hospital Medical Center, Cincinnati
2 Previous Clinical Trials
55 Total Patients Enrolled
1 Trials studying Autism Spectrum Disorder
40 Patients Enrolled for Autism Spectrum Disorder

Eligibility Criteria

Age < 65 · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have been diagnosed with depression and have failed one or more evidence-based antidepressant treatments (e.g

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 1st, 2021

Last Reviewed: October 1st, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

Who else is applying?

What state do they live in?
Pennsylvania50.0%
Missouri25.0%
New York25.0%
How old are they?
18 - 65100.0%
What site did they apply to?
Cincinnati Children's Hospital Medical Center100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%