← Back to Search

Tailored Light Therapy for Dementia

N/A
Waitlist Available
Led By Mariana G Figueiro, PhD
Research Sponsored by Icahn School of Medicine at Mount Sinai
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Mild to moderate Alzheimer's disease and related dementia (ADRD)
Be older than 65 years old
Must not have
Macular degeneration
History of head injury
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline (week 0) and intervention (week 4)
Awards & highlights

Summary

This trial shows that tailored light treatment can improve sleep, reduce depression and reduce agitation in people with Alzheimer's disease and related dementia.

Who is the study for?
This trial is for individuals with mild to moderate Alzheimer's disease and related dementia. It's not suitable for those who are blind, have major organ failure or illness, a history of head injury, uncontrolled hypertension or diabetes, use sleep aid medicine, or have obstructing cataracts or macular degeneration.Check my eligibility
What is being tested?
The study tests whether tailored light treatment can improve sleep efficiency, reduce depression symptoms, and lessen agitation in people with dementia. Participants will receive either an active light intervention designed just for them or a placebo-like inactive one.See study design
What are the potential side effects?
Since the trial involves light therapy rather than medication, side effects may be minimal but could include potential discomfort from the light exposure such as eye strain or headache.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been diagnosed with mild to moderate Alzheimer's or related dementia.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have macular degeneration.
Select...
I have had a head injury in the past.
Select...
My major organs are functioning properly.
Select...
I have cataracts that block my vision.
Select...
I have high blood pressure or diabetes.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline (week 0) and intervention (week 4)
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline (week 0) and intervention (week 4) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Agitation
Depression
Sleep Disturbance
Secondary outcome measures
Actigraphy
Activity of Daily Living
Light/dark patterns

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active InterventionActive Control1 Intervention
Light levels, primary and secondary measurements are obtained after a 4-week intervention period where active lighting is experienced by patients.
Group II: Inactive interventionPlacebo Group1 Intervention
Light levels, primary and secondary measurements are obtained after a 4-week intervention period where an inactive lighting is experienced by patients

Find a Location

Who is running the clinical trial?

National Institute on Aging (NIA)NIH
1,704 Previous Clinical Trials
28,033,212 Total Patients Enrolled
36 Trials studying Depression
28,308 Patients Enrolled for Depression
Icahn School of Medicine at Mount SinaiLead Sponsor
871 Previous Clinical Trials
527,227 Total Patients Enrolled
34 Trials studying Depression
4,324 Patients Enrolled for Depression
Mariana G Figueiro, PhDPrincipal InvestigatorIcahn School of Medicine at Mount Sinai
2 Previous Clinical Trials
76 Total Patients Enrolled

Media Library

Tailored Light Treatment Clinical Trial Eligibility Overview. Trial Name: NCT01816152 — N/A
Depression Research Study Groups: Active Intervention, Inactive intervention
Depression Clinical Trial 2023: Tailored Light Treatment Highlights & Side Effects. Trial Name: NCT01816152 — N/A
Tailored Light Treatment 2023 Treatment Timeline for Medical Study. Trial Name: NCT01816152 — N/A
~8 spots leftby Jul 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top