PECS-1 for Breast Cancer

"A diagnosis of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) will disrupt the social and occupational lives of many women. It is likely many will not live long enough to experience the full consequences of their personal cancer experience. Some women will be reassured by their diagnosis: it helps them accept the realities of their illness and gives them a sense of their own power. Most women will, however, experience challenges of adjustment to their illness and their treatment, including the loss of a spouse, a reduction in social activities and participation, work limitation, treatment discontinuance, and grief." - Anonymous Online Contributor

"The cause of breast cancer is still unknown. There is evidence that genetics plays a role, and studies are ongoing to determine whether other factors such as environmental or lifestyle factors play a large role in causing breast cancer." - Anonymous Online Contributor

"Although our data suggest improvement in a minority of women in this population, it will be difficult to establish whether or not breast cancer is curable." - Anonymous Online Contributor

"Women in the United States experience an average of 79,600 new invasive [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) cases a year. Approximately 6,000 women are diagnosed with breast cancer each year. Breast cancer is the most common form of cancer among women (22.1%), followed by colorectal (11.7%) and colorectal carcinoma (9.3%). Most women who develop breast cancer (70.8%) are older than age 65 years. The average age at diagnosis of breast cancer is 61.1 years. A small percentage of breast cancer develops from a hereditary precondition." - Anonymous Online Contributor

"Early signs of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) include breast mass, enlargement, warmth, and bleeding. Painful, swollen lymph nodes also indicate advanced disease that requires systemic therapy such as chemotherapy or hormonal treatment. A lump in the breast is an inconsistent sign that requires medical evaluation.\n" - Anonymous Online Contributor

"Most cases of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) are discovered before symptoms are noticed. People are also less likely to get treatment if they have an income of under $45,000 per year. Patients with estrogen receptor-positive breast cancer are more likely to obtain surgery. Radiation is associated with a decreased risk of developing other cancers, such as multiple myeloma, lung cancer, or leukemia. The use of a mammogram and breast self-examination are associated with a 15% decrease in breast cancer, but the number of people undergoing these preventive measures is insufficient to reduce overall breast cancer rates." - Anonymous Online Contributor

"The average age that breast cancer occurs in the United States is 54.4. In the period 1992-2001, the age at diagnosis increased from 53.0 years in 1992 to 54.4 years in 2000 (r=.25, p=0.011). Older age at diagnosis (52.6 years in 2005) was associated with higher grade (p=0.038), N stage (p=0.014), and distant metastasis (p=0.016). The incidence rate of breast cancer was inversely related to time since diagnosis (r=.22, p=0.001). Women from the most recent cohorts (2005) were significantly younger than controls from the prior decade (1989) (55." - Anonymous Online Contributor

"Recent findings of this study suggest that there is a significant genetic predisposition to breast cancer, although the mechanism underlying this predisposition is not well understood and deserves further research." - Anonymous Online Contributor

"Pecs-1 has been found to significantly increase HDL-cholesterol with no adverse effects. The risk of cholesterol changes in the body can be seen to be lower than that of placebo without significant effect on HDL-cholesterol levels." - Anonymous Online Contributor

"Although there is considerable variability regarding the efficacy of antiestrogen therapies, adjuvant chemotherapy is one of the most important determinants of outcome for breast cancer, and many advances in this area are ongoing." - Anonymous Online Contributor

"The pecs-1 group experienced a significantly more rapid decline in neutrophils and less change in LY per liter over the first 10 weeks of treatment, but there was no difference in other neutrophil parameters and hemoglobin counts. The group received a lower dose of cytarabine per course and experienced fewer chemotherapy-related adverse events." - Anonymous Online Contributor

"PEPS1 is a key factor in the cellular stress response that can also regulate other cellular processes important for cellular homeostasis and viability. It was first identified in mice by two labs independently in different mammalian cell lines. It has been shown with numerous in vitro and in vivo studies to function by altering a wide range of biological and pathological processes. It was later shown to have an anti-apoptotic role in human cancers. Thus, the peptide might be developed as a novel anti-cancer treatment." - Anonymous Online Contributor