Erector Spinae Block for Post-Operative Pain in Breast Cancer Surgery
Trial Summary
Do I need to stop my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. However, if you are using chronic opioids (30 mg or more of oxycodone per day), you would not be eligible to participate.
What data supports the effectiveness of the treatment Erector Spinae Block for post-operative pain in breast cancer surgery?
Is the Erector Spinae Block safe for humans?
How does the erector spinae plane block treatment differ from other treatments for post-operative pain in breast cancer surgery?
The erector spinae plane block (ESPB) is a novel regional anesthesia technique that provides pain relief by blocking nerve signals in a specific area of the back, which can reduce the need for opioids and their associated side effects. Unlike traditional pain management methods, ESPB targets a wide range of nerve roots from T1 to L3, offering effective pain control for breast surgery patients.12348
What is the purpose of this trial?
Regional anaesthesia combined with general anaesthesia has become common in the perioperative management of breast cancer surgery patients. Regional techniques have been recognised to provide excellent post-operative analgesia. It enhances multi-modal analgesia regimes while being opioid sparing, reducing incidence of post-operative nausea and vomiting and allowing earlier mobilisation/discharge and improving treatment success. Therefore identifying the correct regional anaesthetic technique for this group of patients is important in providing optimum peri-operative care.
Research Team
Richard Brull, MD
Principal Investigator
Women's College Hospital
Eligibility Criteria
This trial is for breast cancer surgery patients with an ASA classification of I-III and a BMI under 35. It's suitable for those having day surgery without severe respiratory or cardiac conditions, no history of significant chest surgeries (except lumpectomy), and not on high-dose opioids. Participants mustn't have allergies to local anaesthetics, be pregnant/nursing, or unable to consent.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either an ESP block or a sham block during ambulatory breast cancer surgery
Immediate Postoperative Recovery
Participants are monitored for quality of recovery and acute postoperative pain within 24 hours post-surgery
Follow-up
Participants are monitored for postoperative pain, opioid consumption, and block-related complications
Treatment Details
Interventions
- Erector Spinae Block
- Placebo Block
Find a Clinic Near You
Who Is Running the Clinical Trial?
Women's College Hospital
Lead Sponsor