Pain Management Techniques for Collarbone Fracture

(CERPICO Trial)

Enrolling by invitation at 1 trial location
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Naval Medical Center Camp Lejeune
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests two methods to manage pain after clavicle (collarbone) surgery. One method uses a cervical plexus block, guided by ultrasound, while the other involves local pain relief directly from the surgeon. The goal is to determine which method more effectively reduces pain and the need for pain medication. The trial seeks adults scheduled for collarbone or nearby joint surgery who have not recently used opioids. As an unphased trial, it offers participants the chance to contribute to innovative pain management research that could enhance surgical recovery for future patients.

Will I have to stop taking my current medications?

The trial information does not specify if you need to stop taking your current medications. However, if you have used opioids in the last 30 days for reasons unrelated to your clavicle, AC joint, or CC ligament, you may not be eligible to participate.

What prior data suggests that these pain management techniques are safe for clavicle fracture surgery?

Research has shown that the cervical plexus block safely and effectively manages pain after surgery for a broken collarbone. Studies have found that this anesthesia provides good pain relief and aids recovery. It is well-tolerated, with no major safety issues reported in these studies.

For local infiltration analgesia, evidence also supports its safety in collarbone surgeries. Research indicates it can be used reliably without major complications, helping manage pain during and after surgery. Both treatments have been used successfully in past surgeries, with no significant safety concerns identified.

Overall, both the cervical plexus block and local infiltration analgesia are safe methods for managing pain in collarbone surgeries.12345

Why are researchers excited about this trial?

Researchers are excited about the new pain management techniques for collarbone fractures because they offer innovative approaches to anesthesia. Unlike traditional methods that often rely on general anesthesia or systemic pain medications, the cervical plexus block specifically targets the nerves in the neck region using ultrasound guidance. This precise delivery can lead to more effective pain control with potentially fewer side effects and quicker recovery times. Additionally, the comparison with local infiltration analgesia aims to fine-tune pain relief strategies, offering insights into which method could provide better outcomes for patients.

What evidence suggests that this trial's treatments could be effective for managing pain after clavicle surgery?

This trial will compare two pain management techniques for collarbone fracture surgery: the cervical plexus block and local infiltration analgesia. Research has shown that a cervical plexus block, which participants in one arm of this trial may receive, is promising for pain relief after collarbone surgery. Studies have found that it effectively controls pain while reducing the need for opioids. This method uses ultrasound to precisely target nerves, easing pain without affecting muscle movement. In contrast, local infiltration analgesia, which participants in another arm of this trial may receive, involves injecting pain relief directly at the surgery site. While it helps manage pain, some research suggests it might not be as effective as the cervical plexus block. Overall, these findings support using cervical plexus blocks for better pain management after collarbone surgery.36789

Who Is on the Research Team?

CL

CDR Lee, MD

Principal Investigator

DHA/MD365

Are You a Good Fit for This Trial?

This trial is for individuals with shoulder injuries like separated shoulders or collarbone fractures. It's particularly focused on military service members who have a higher incidence of these injuries and may require surgery. Participants must be eligible for surgical intervention and interested in postoperative pain management options.

Inclusion Criteria

My health is good to moderately impaired.
I am scheduled for surgery on my shoulder area at NMCL.

Exclusion Criteria

I need surgery urgently.
Prior anaphylactic reaction or known intolerance to study medications
I have used opioids in the last month not for shoulder-related pain.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Preoperative Preparation

Standardized anesthetic plan including preoperative anxiolysis and induction of anesthesia

1 day
1 visit (in-person)

Surgical Procedure

Ultrasound-guided intermediate cervical plexus block or local infiltration analgesia performed during clavicle surgery

1 day
1 visit (in-person)

Postoperative Recovery

Monitoring in PACU with pain management and data collection

3-4 hours
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including post-discharge pain management

1-2 days

What Are the Treatments Tested in This Trial?

Interventions

  • Cervical Plexus Block
  • Local Infiltration Analgesia
Trial Overview The CERPICO study is testing two types of local anesthesia to manage pain after clavicle surgery: cervical plexus block versus local infiltration analgesia (LIA). The goal is to see which method provides better pain relief and reduces the need for opioids after surgery.
How Is the Trial Designed?
2Treatment groups
Active Control
Group I: ultrasound guided cervical plexus blockActive Control2 Interventions
Group II: local infiltration analgesiaActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Naval Medical Center Camp Lejeune

Lead Sponsor

Trials
3
Recruited
170+

Citations

Regional Anesthetic and Analgesic Techniques for ...Cervical plexus block can provide motor-sparing analgesia following clavicle surgery. Promising alternatives include the clavipectoral block, which is a novel ...
Ultrasound-guided superficial cervical plexus block for ...We describe an innovative case of cancer-related clavicle pain successfully managed with a superficial cervical plexus block in an opioid-intolerant patient.
Ultrasound-Guided Clavipectoral Plane Block for ...The ultrasound-guided CPB may be a safe and effective analgesic strategy for uncomplicated clavicle fractures in the ED.
Efficacy Comparison Between Interscalene Block with and ...Cervical and interscalene brachial plexus blocks resulted in minimal pain and opioid use (17). Consequently, RA approaches were as efficient as ...
Regional Anesthesia for Clavicle Fracture SurgeryHowever, our review showed that intermediate cervical plexus or combined cervical plexus blocks provided more effective analgesia and had a ...
6.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/33197587/
Regional anesthesia for clavicle fracture surgery is safe ...Regional anesthesia using a combined brachial plexus and modified superficial cervical plexus block is a reliable, efficacious technique.
Ultrasound-Guided Combined Interscalene-Cervical ...The ultrasound-guided combined interscalene-cervical plexus block was a successful and effective regional anesthesia method in clavicular fracture repair.
Superficial Cervical Plexus Block With Either Clavipectoral ...This study aims to evaluate and compare the efficacy and safety of ultrasound guided superficial cervical plexus block (SCPB) with either clavipectoral fascial ...
EP157 Interscalene and superficial cervical plexus blocks ...Conclusions Interscalene and superficial cervical plexus blocks provided adequate anesthesia and enhanced postoperative outcome. The combined techniques may be ...
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security