Lidocaine Patch for Overactive Bladder
Trial Summary
What is the purpose of this trial?
This trial tests if a lidocaine patch can reduce pain for patients undergoing a PNE procedure. The patch numbs the lower back to make the procedure less painful. Patients' pain levels and satisfaction will be measured. Lidocaine patches have been used to treat various types of pain, including nerve pain, pain after shingles, and pain after surgery, with mixed results.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the lidocaine patch treatment for overactive bladder?
Is the lidocaine patch safe for humans?
How does the lidocaine patch treatment for overactive bladder differ from other treatments?
The lidocaine patch for overactive bladder is unique because it uses a local anesthetic to block nerve signals in the bladder, potentially reducing symptoms without affecting bladder muscle contractions. This is different from standard treatments like anticholinergics, which reduce bladder muscle activity, or botulinum toxin injections, which require more invasive administration.125710
Eligibility Criteria
This trial is for women over 18 with overactive bladder (OAB) who are scheduled for a nerve evaluation procedure without fluoroscopy and have no allergies to lidocaine or adhesives. It's not suitable for those not eligible for sacral neuromodulation therapy, pregnant women, or those getting the procedure for chronic pain.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a 4% lidocaine patch or placebo patch 30 minutes prior to the PNE procedure
Follow-up
Participants are monitored for safety and effectiveness after the PNE procedure, including adverse events and satisfaction scores
Long-term Follow-up
Rate of progression to permanent SNS implantation is assessed
Treatment Details
Interventions
- Lidocaine patch
- Placebo
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Louisville
Lead Sponsor