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Behavioural Intervention

Baduanjin Exercise for Cognitive Decline (BDJ Trial)

N/A
Recruiting
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
50 - 80 years old
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3, 6, 9 months
Awards & highlights

BDJ Trial Summary

This trial looks at whether Baduanjin, a type of mind-body exercise, can improve cognitive function, brain connectivity, and brain structure in people with subjective cognitive decline.

Who is the study for?
This trial is for adults aged 50-80 with subjective cognitive decline, who have normal memory scores and no significant forgetfulness. They should not have depression, other diseases causing cognitive issues, or a history of severe mental health conditions. Participants must be able to engage in a 6-month exercise program with follow-up and have an informant to confirm their memory concerns.Check my eligibility
What is being tested?
The study tests the effects of Baduanjin exercise on brain function and structure in individuals feeling they've had a decline in memory but are still within normal ranges on standard tests. It compares this traditional mind-body practice against a cognitive fitness program to see if it can prevent age-related cognitive issues.See study design
What are the potential side effects?
Since Baduanjin is a gentle form of exercise combining movement and meditation, side effects might include muscle soreness or strain from new physical activities. The cognitive fitness program may cause fatigue or frustration but generally has minimal risks.

BDJ Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 50 and 80 years old.

BDJ Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3, 6, 9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3, 6, 9 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Alzheimer Disease Cooperative Study- Preclinical Alzheimer (ADCS-PACC) Cognitive Composite
Functional connectivity of hippocampus and DLPFC
Secondary outcome measures
Beck Anxiety Inventory (BAI)
Blood markers
Brain morphometry
+11 more

BDJ Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: BaduanjinExperimental Treatment1 Intervention
This group will participate in the Baduanjin exercise intervention for 24 weeks (three times/week for the first three months and two times/week for the last three months).
Group II: Cognitive Fitness ProgramActive Control1 Intervention
This group will participate in the Cognitive Fitness Program intervention for 24 weeks (three times/week for the first three months and two times/week for the last three months).

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,933 Previous Clinical Trials
13,198,361 Total Patients Enrolled
2 Trials studying Cognitive Decline
161 Patients Enrolled for Cognitive Decline

Media Library

Baduanjin Exercise (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04009382 — N/A
Cognitive Decline Research Study Groups: Baduanjin, Cognitive Fitness Program
Cognitive Decline Clinical Trial 2023: Baduanjin Exercise Highlights & Side Effects. Trial Name: NCT04009382 — N/A
Baduanjin Exercise (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04009382 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To whom is this clinical trial open for enrollment?

"Eligibility for this trial requires the patient to be between 50 and 80 years old, as well as demonstrate cognitive decline. This clinical study is accepting around 120 recruits in total."

Answered by AI

What is the size of the sample population participating in this experiment?

"Affirmative. Clinicaltrials.gov shows that this research is actively recruiting patients, having first been posted on August 31st 2020 and most recently updated on June 23rd 2021. The study needs to recruit 120 individuals from one medical centre."

Answered by AI

Are any openings available for individuals wishing to participate in this clinical experiment?

"Affirmative. Clinicaltrials.gov lists this clinical trial as currently seeking participants; the study was initial posted on August 31st 2020, and revised most recently on June 23rd 2021. The research is hoping to enroll 120 individuals from 1 site."

Answered by AI

What results are researchers hoping to achieve from this medical experiment?

"The purpose of this trial, which will be assessed at baseline, 3 months and 6 months is to determine the impact of exercise on Alzheimer Disease Cooperative Study- Preclinical Alzheimer (ADCS-PACC) Cognitive Composite. Secondary aims include measuring changes in brain grey matter volume via MRI scanning, assessing levels of anxiety using Beck Anxiety Inventory (BAI), and establishing an oral version of the Digit Symbol Substitution Test (SDMT)."

Answered by AI

Is the elderly population being considered for this research endeavor?

"This clinical trial is accepting geriatric participants that are over 50 years of age but not exceeding 80 years."

Answered by AI

Who else is applying?

What state do they live in?
Tennessee
New York
How old are they?
65+
What site did they apply to?
Massachusetts General Hospital
What portion of applicants met pre-screening criteria?
Did not meet criteria
~0 spots leftby Apr 2024