Cognitive + Exercise Training for Cognitive Decline in Renal Disease
(IMPCT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This is a randomized, controlled trial to slow cognitive decline in adults undergoing hemodialysis (HD). The investigators will test three interventions cognitive training (CT), exercise training (ET), and combined cognitive and exercise training (CT+ET) relative to standard of care (SC).
Who Is on the Research Team?
Aarti Mathur, MD, PhD
Principal Investigator
Johns Hopkins University
Are You a Good Fit for This Trial?
This trial is for English-speaking adults over 18 who started hemodialysis between 3 months to 3 years ago at participating centers. It's not for those with severe heart or lung conditions, hepatitis B, mobility issues due to musculoskeletal conditions or amputations, blindness, orthopedic disorders worsened by exercise, or those pregnant or incarcerated.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo cognitive training, exercise training, or combined cognitive and exercise training during hemodialysis sessions
Follow-up
Participants are monitored for safety and effectiveness after treatment
Long-term Follow-up
Mortality and other long-term outcomes are monitored
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive training
- Combined cognitive and exercise training
- Exercise training
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johns Hopkins University
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator