~102 spots leftby Apr 2026

Electronic Symptom Management for Advanced Cancer

Palo Alto (17 mi)
Overseen byKathryn Schmitz, PhD
Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: N/A
Recruiting
Sponsor: Milton S. Hershey Medical Center
No Placebo Group

Trial Summary

What is the purpose of this trial?This trial is testing Nurse AMIE 3.0, a tablet-based program, to help stage 3 and 4 cancer patients in rural areas manage their symptoms. The program aims to provide remote support to improve their overall survival.
Is Nurse AMIE a promising treatment for managing symptoms in advanced cancer patients?Yes, Nurse AMIE is a promising treatment because it uses technology to help manage symptoms in real-time, making it easier for patients to get the care they need quickly. This can improve the quality of care for people with advanced cancer, especially those in remote areas.24111213
What safety data exists for the Electronic Symptom Management for Advanced Cancer treatment?The provided research does not directly address safety data for the Electronic Symptom Management for Advanced Cancer treatment or its other names like Nurse AMIE. The studies focus on educational needs for adverse events in immunotherapy, the use of patient diaries during chemotherapy, and the role of nurses in managing adverse events in melanoma therapies. None of these specifically evaluate the safety of the Electronic Symptom Management system.7891014
Do I have to stop taking my current medications for this trial?The trial protocol does not specify whether you need to stop taking your current medications. It seems likely that you can continue your current treatments, as the trial focuses on symptom management for advanced cancer.
What data supports the idea that Electronic Symptom Management for Advanced Cancer is an effective treatment?The available research shows that specially trained nurses can significantly improve the quality of life for patients with advanced cancer by managing pain effectively. In a study, patients who received home visits from nurse practitioners experienced better pain control in the last 90 days of life compared to those who did not receive such visits. This suggests that having dedicated nursing support, similar to Electronic Symptom Management for Advanced Cancer, can be beneficial in managing symptoms and improving patient outcomes.135615

Eligibility Criteria

This trial is for adults with advanced stage 3 or 4 cancer, living in certain rural areas, who are undergoing treatment (not just palliative care). They must have a life expectancy of at least 6 months, be able to use a phone for check-ins, and not be part of other supportive care studies.

Treatment Details

Nurse AMIE is an electronic system designed to help manage symptoms in cancer patients. The study compares its effectiveness on survival rates against usual care without this technology among those living in rural settings.
2Treatment groups
Experimental Treatment
Active Control
Group I: Nurse AMIE Supportive Care InterventionExperimental Treatment1 Intervention
Participants in the intervention arm will receive the computer tablet with the Nurse AMIE program. Nurse AMIE will assess their symptoms daily and provide an intervention to help manage their symptoms.
Group II: Usual CareActive Control1 Intervention
Participants in the usual care arm will receive a book with some supportive care educational materials and recommendations.

Find a clinic near you

Research locations nearbySelect from list below to view details:
Mount Nittany Medical CenterState College, PA
UPMC-ButlerButler, PA
West Virginia UniversityMorgantown, WV
UPMC - NorthwestSeneca, PA
More Trial Locations
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Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor
University of PittsburghLead Sponsor
National Cancer Institute (NCI)Collaborator
West Virginia UniversityCollaborator
Mount Nittany Medical CenterCollaborator
Penn State UniversityCollaborator

References

Prediction and management of pain in patients with advanced cancer. [2019]In a prospective controlled study, patients with incurable cancer and an estimated prognosis of three months to one year were allocated to two patient groups for evaluation of supportive interventions. One group, called "intensive," received home visits by a nurse practitioner acting as an extension of a multidisciplinary team; the other, termed "nonintensive," did not receive such visits. Both patient groups were periodically evaluated in their homes by an observer and by self-ratings, to measure changes in quality of life as their disease progressed. Several methodologic problems were identified, which have implications for future research. Pain problems later in the course of cancer seem to be predictable in those patients with higher scores on the Cornell Medical Index M-R scales (greater emotional disturbance) and on the Rotter Locus of Control (I-E) scale (expectation of more external control of self). The study also found that the home visiting nurse practitioners, specially trained in pain treatment, improved pain control in the "intensive" group of patients over the last 90 days of life, when pain was an increasingly major problem. Such nurses can significantly improve the quality of life for patients dying outside of institutions.
Perceptions of the use of a remote monitoring system in patients receiving palliative care at home. [2017]In remote communities, where frequent face-to-face contact with health professionals may be difficult, the ongoing review and management of symptoms--a fundamental part of good palliative care--can be difficult to achieve. Telecare and other developments in information technology are increasingly being sought as a means of addressing shifting population demographics and rising demands on stretched health services, and may help in providing a system which allows patients to report their symptoms as they are happening. This may be one way of enhancing symptom management and improving quality of care at the end of life. A study testing the feasibility of using mobile phone-based technology (Advanced Symptom Management System in Palliative Care (ASyMSp)) to monitor and manage symptoms reported by patients being cared for at home in the advanced stages of their illness was carried out in two rural communities in the north of Scotland. The results of this study show that the system was usable and acceptable to patients and the health professionals who cared for them.
Oncology nursing support for safe and effective use of eribulin in metastatic breast cancer. [2021]Nurse practitioners play important roles in breast cancer prevention, early detection, therapeutic efficacy, and surveillance. Assessment of a patient's health status is part of the nine nurse practitioner core competencies updated in 2012 by the National Organization of Nurse Practitioner Faculties. Although adverse events are common in treatment for metastatic breast cancer (MBC), proactive management strategies can limit the number and/or severity of adverse events. Additionally, knowledge of common metastatic sites and clinical signs/symptoms of recurrence provides one of the first-line strategies for successful treatment. We review five case studies of women with MBC who were managed successfully with eribulin mesylate in late lines of therapy after at least two chemotherapeutic regimens for advanced breast cancer that included both an anthracycline and a taxane in either the adjuvant or metastatic setting.
Palliative care at the end of life. [2019]To describe the process of symptom management in the care of oncology patients with advanced cancer.
Improving End-of-Life Care Prognostic Discussions: Role of Advanced Practice Nurses. [2016]Research has validated the desire of patients and families for ongoing prognostic information; however, few conversations occur before patients reach the advanced stages of their disease trajectory. Physician hesitance and delay in discussing unfavorable prognoses deny patients and families optimal time to prepare for critical decision making. Advanced practice registered nurses can play a crucial, complementary role with the critical care interdisciplinary team to implement strategies to improve communication about prognosis and end of life with patients and families. Clinicians should discuss deterioration in disease-specific characteristics and changes (decline) in functional status. Functional status can serve as an accurate guide for forecasting prognosis, particularly in patients with heart failure, stroke, chronic lung disease, and end-stage renal disease. This article provides an overview of effective intensive care unit prognostic systems and discusses barriers and opportunities for nurses to use evidence-based knowledge related to disease trajectory and prognosis to improve communication and the quality of palliative and end-of-life care for patients.
Advanced breast cancer clinical nursing curriculum: review and recommendations. [2018]The needs and concerns of patients with advanced breast cancer are changing at every phase of the care intervention. Management and coordination of hospital resources and services are also steadily evolving. The objective of the present expert report is to define a new oncology nursing role specialising in advanced breast cancer, to help guide patients throughout the whole healthcare itinerary.
A Mobile App to Stabilize Daily Functional Activity of Breast Cancer Patients in Collaboration With the Physician: A Randomized Controlled Clinical Trial. [2022]The well-being of breast cancer patients and reporting of adverse events require close monitoring. Mobile apps allow continuous recording of disease- and medication-related symptoms in patients undergoing chemotherapy.
Collaborative Care in Melanoma: The Essential Role of the Nurse . [2018]This article provides perspective from medical oncologists on the importance of this supplement from the Melanoma Nursing Initiative. The authors (a) delineate the challenges inherent in addressing adverse event (AE) management with newer melanoma therapies, particularly in the community setting; (b) illustrate how advanced practice providers with extensive clinical trial experience in melanoma are in a key position to set the agenda and educate colleagues on best practices in AE management; and
Advances in Melanoma: The Rationale for the Melanoma Nursing Initiative . [2018]This article provides an overview of this supplement, outlining the needs assessment process the Melanoma Nursing Initiative (MNI) used to determine the immunotherapy and targeted therapy topics for discussion as well as the process for developing the consensus statements. The article provides specific discussion of a unique feature of the MNI, the care step pathways (CSPs) for management of adverse events (AEs) associated with melanoma therapies, and looks to the future in terms of the potential benefits of engaging and enabling oncology nurses to adopt a standardized approach to AE management and adherence promotion for melanoma therapies.
10.United Statespubmed.ncbi.nlm.nih.gov
Implementation and Use of a Patient Symptom Diary During Chemotherapy: A Mixed-Methods Evaluation of the Nurse Perspective. [2018]To gain a deeper understanding of nurses' experience working with a patient diary for tracking and treating side effects during chemotherapy. .
Quality of telephone nursing services for adults with cancer and related non-emergent visits to the emergency department. [2020]A quality improvement project was conducted to determine the quality of telephone nursing for patients with cancer symptoms. Eligible patients were ones who telephoned the nurse about cancer symptom(s) within four weeks prior to an emergency department (ED) visit not requiring hospital admission. Experienced oncology nurses extracting data indicated appropriateness of ED visits and opportunities for improvement. The Symptom Management Analysis Tool was used to analyze nurse documentation. For 77 patients, 87% ED visits occurred within four days of calls about symptoms (e.g., pain, breathlessness, constipation, diarrhea, nausea/vomiting) and 91% could have been managed by more complete telephone assessment and/or an urgent clinic visit. Quality of nurse documentation revealed few patients were assessed adequately (38%), received any symptom-specific medication review (49%), or were guided in self-care strategies (17%). There was low-quality telephone symptom management by nurses and a need for alternative options for patients requiring urgent face-to-face assessments. Our findings highlight a gap in use of guidelines for informing telephone symptom management.
Real-time symptom management in the context of a remote symptom-monitoring system: prospective process evaluation and cross-sectional survey to explore clinical relevance. [2021]Electronic systems for remotely monitoring symptoms during systemic anticancer treatment are increasingly being used. Some of these systems have features triggering alerts to healthcare professionals for worsening and/or severe symptoms, enabling real-time symptom management. This study aimed at exploring the characteristics and process of real-time alert management as well as its clinical relevance as perceived by healthcare professionals.
Web and mobile-based symptom management interventions for physical symptoms of people with advanced cancer: A systematic review and meta-analysis. [2021]Symptom management is a critical aspect of comprehensive palliative care for people with advanced cancer. Web and mobile-based applications are promising e-Health modalities that can facilitate timely access to symptom management interventions for this population.
14.United Statespubmed.ncbi.nlm.nih.gov
Exploring the educational needs for severe immune-related adverse events of PD-1/PD-L1 inhibitors in advanced lung cancer: A single-center observational study. [2022]With the expanded use of immunotherapy in medical oncology, effective patient education regarding immune-related adverse events (irAEs) is crucial for oncology nursing. Therefore, this study aimed to identify educational needs for preventing unscheduled hospitalizations due to severe irAEs.
Professional competencies of oncology nurses: Recognizing advanced practice in nursing. [2023]To identify the competency profile of advanced practice nurses involved in the care process of cancer patients.