Your session is about to expire
← Back to Search
Neurofeedback
Neurofeedback for Cerebellar Ataxia (fMRI Trial)
N/A
Waitlist Available
Led By Cherie Marvel, PhD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
18-100 years of age
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and at-home sessions (10 minutes/day), up to 23 days
Awards & highlights
fMRI Trial Summary
This trial will study whether real-time functional magnetic resonance imaging neurofeedback in conjunction with motor imagery can help people with cerebellar ataxia recover some motor function.
Who is the study for?
This trial is for adults aged 18-100, who are right-handed and have at least an 8th-grade education. It's not suitable for those with MRI contraindications like metal implants, pacemakers, or claustrophobia; people with psychiatric disorders, severe medical conditions, neurological issues like stroke or epilepsy; pregnant women; those with significant head injuries; or without home internet to complete part of the study.Check my eligibility
What is being tested?
The study tests if a special type of brain scan feedback called rt-fMRI NF combined with imagining movements can help improve motor function in people with cerebellar ataxia. Healthy adults' data will be used as a comparison.See study design
What are the potential side effects?
There may be minimal side effects related to the MRI procedure such as discomfort from lying still and loud noises during scanning. The neurofeedback treatment itself is non-invasive and typically does not produce side effects.
fMRI Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 100 years old.
fMRI Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and at-home sessions (10 minutes/day), up to 23 days
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and at-home sessions (10 minutes/day), up to 23 days
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in at-home overt tapping accuracy as assessed by finger tapping to a flashing cue at 1Hz speed
Change in at-home overt tapping accuracy as assessed by finger tapping to a flashing cue at 4Hz speed
Change in overt tapping accuracy as assessed by finger tapping to a flashing cue at 1Hz speed
+1 moreSecondary outcome measures
The correlation between MRI BOLD and finger tapping accuracy to a flashing cue at 1Hz as assessed by a correlation coefficient
The correlation between MRI BOLD and finger tapping accuracy to a flashing cue at 4Hz as assessed by a correlation coefficient
The correlation between the ICARS and imagery accuracy of the slider bar from target on the MRI task as assessed by a correlation coefficient
+1 morefMRI Trial Design
2Treatment groups
Experimental Treatment
Group I: Real time neurofeedback with taskExperimental Treatment1 Intervention
Participants will undergo a real-time fMRI scan during which two distinct tasks will be performed.
Group II: Overt tapping and/or motor imagery practiceExperimental Treatment1 Intervention
Participants will undergo an overt tapping task at baseline. Participants are assigned to a group where they will then perform respective motor and/or imagery tasks at home for 3 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
At-home therapy
2023
N/A
~40
Neurofeedback treatment
2014
N/A
~190
Find a Location
Who is running the clinical trial?
Johns Hopkins Discovery AwardUNKNOWN
Johns Hopkins UniversityLead Sponsor
2,256 Previous Clinical Trials
14,820,059 Total Patients Enrolled
Virginia Polytechnic Institute and State UniversityOTHER
141 Previous Clinical Trials
27,754 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I had a head injury that made me unconscious for more than 5 minutes or caused lasting brain effects.I can stop taking certain medications that affect my brain function before tests if needed.You have a history of serious mental health issues or problems with alcohol or drugs.I do not have severe or unstable illnesses like stroke or epilepsy.I am between 18 and 100 years old.You are right-handed.
Research Study Groups:
This trial has the following groups:- Group 1: Real time neurofeedback with task
- Group 2: Overt tapping and/or motor imagery practice
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How can I volunteer for this research project?
"This research is only open to individuals who have hypermetria and are between 18-100 years old. They hope to enroll ~30 people in total."
Answered by AI
Are people currently being signed up for this clinical trial?
"This specific study is no longer recruiting patients, as noted on clinicaltrials.gov. The trial was originally posted December 1st, 2022 and last updated August 19th, 20202. Although this particular trial has completed recruitment, there are still 937 other trials currently searching for participants."
Answered by AI
What goals does this experiment seek to realize?
"The primary outcome of this trial will be assessed by measuring changes in overt tapping accuracy, as determined by finger tapping to a flashing cue at 4Hz speed. Secondary outcomes include the correlation between MRI BOLD and finger tapping accuracy to a flashing cue at 1Hz, as well as the correlation between the KVIQ and imagery accuracy of the slider bar from target on the MRI task."
Answered by AI
Will this experiment be testing middle-aged adults?
"According to the eligibility requirements specified by this clinical trial, patients must be aged 18 to 100. There are 71 similar studies for people under 18 and 426 for patients over 65."
Answered by AI
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger