Prehabilitation for Living Donor Liver Transplantation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University Health Network, Toronto, Canada
Living Donor Liver Transplantation
Prehabilitation - Other
Eligibility
Any Age
All Sexes
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Study Summary

to determine if a Phase III RCT of prehab vs usual care for LLDs is feasible (including rates of recruitment, adherence, adverse events, and attrition); to determine what, if any, intervention or trial modifications are warranted for a Phase III RCT; and, to explore estimates of efficacy among donor-centered outcomes (e.g., quality of life, physical function, satisfaction with care) that may form the basis for sample size calculations of a Phase III RCT.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Living Donor Liver Transplantation

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: 12 Weeks

12 Weeks
Feasibility Outcomes
Hospital readmission
Post operative length of stay (LOS)
Surgical and post-operative complications

Trial Safety

Safety Progress

1 of 3

Other trials for Living Donor Liver Transplantation

Trial Design

2 Treatment Groups

Usual Care
1 of 2
Prehabilitation
1 of 2
Active Control
Experimental Treatment

30 Total Participants · 2 Treatment Groups

Primary Treatment: Prehabilitation · No Placebo Group · N/A

Prehabilitation
Other
Experimental Group · 1 Intervention: Prehabilitation · Intervention Types: Other
Usual CareNoIntervention Group · 1 Intervention: Usual Care · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 weeks
Closest Location: University Health Network · Toronto, Canada
Photo of Toronto 1Photo of Toronto 2Photo of Toronto 3
2005First Recorded Clinical Trial
1 TrialsResearching Living Donor Liver Transplantation
271 CompletedClinical Trials

Who is running the clinical trial?

University Health Network, TorontoLead Sponsor
1,351 Previous Clinical Trials
471,603 Total Patients Enrolled

Eligibility Criteria

Age Any Age · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a minimum of 28 days prior to scheduled LDLT.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.