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plethysmography for Friedreich Ataxia

N/A
Waitlist Available
Led By Stephen Chan, MD, PhD
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2-4 hours
Awards & highlights

Study Summary

This trial will study the effects of reduced levels of frataxin on different types of endothelial cells.

Eligible Conditions
  • Friedreich Ataxia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2-4 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2-4 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
vasomotor tone

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Test groupExperimental Treatment1 Intervention
Endothelial dysfunction will be tested using Strain-gauge plethysmography to measure forearm blood flow during infusions of acetylcholine [ACh] and sodium nitroprusside [SNP]
Group II: Control groupActive Control1 Intervention
Endothelial dysfunction will be tested using Strain-gauge plethysmography to measure forearm blood flow during infusions of acetylcholine [ACh] and sodium nitroprusside [SNP]
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
plethysmography
2016
N/A
~60

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,722 Previous Clinical Trials
16,343,041 Total Patients Enrolled
1 Trials studying Friedreich Ataxia
13 Patients Enrolled for Friedreich Ataxia
Friedreich's Ataxia Research AllianceOTHER
16 Previous Clinical Trials
5,941 Total Patients Enrolled
16 Trials studying Friedreich Ataxia
5,941 Patients Enrolled for Friedreich Ataxia
Stephen Chan, MD, PhDPrincipal InvestigatorUniversity of Pittsburgh

Media Library

Plethysmography (Other) Clinical Trial Eligibility Overview. Trial Name: NCT04649866 — N/A
Friedreich Ataxia Research Study Groups: Test group, Control group
Friedreich Ataxia Clinical Trial 2023: Plethysmography Highlights & Side Effects. Trial Name: NCT04649866 — N/A
Plethysmography (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04649866 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any open opportunities to participate in this research endeavor?

"Affirmative, clinicaltrials.gov confirms the ongoing recruitment for this medical trial which was originally posted on February 15th 2021 and updated as recently as January 27th 2022. The study is seeking to fill 6 spots at a single location."

Answered by AI

Is participation in this experiment an available option?

"This clinical trial is enrolling 6 patients suffering from Friedreich Ataxia, aged between 18 and 79. All applicants must meet the minimum age requirement of 18 years old in order to be considered for participation."

Answered by AI

How many participants are enrolled in this clinical experiment?

"Affirmative. Per the information that is visible on clinicaltrials.gov, this investigation has been publicly accessible since February 15th 2021 and was most recently revised in January 27th 2022. It's recruiting 6 patients at a single site for enrolment."

Answered by AI

Are adolescents below the age of 25 eligible to participate in this experiment?

"This medical trial adheres to an age range of 18-79, with the necessary qualifications for enrollment being a minimum of 18 years old."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Coronary Artery Disease in Patients With Friedreich's Ataxia
Stephen Y. Chan 2021. "Coronary Artery Disease in Patients With Friedreich's Ataxia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04649866.
~2 spots leftby Apr 2025
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