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Humidity-ramp protocol for Heat Stress

N/A

Waitlist Available

Led By Glen P Kenny, PhD

Research Sponsored by University of Ottawa

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during the ramp protocol (up to 2.5 hours)

Awards & highlights

Study Summary

This trial investigates the ability of ramping protocols to determine the environmental limits of compensability, the point at which people can no longer stay cool due to climate change.

Eligible Conditions

Heat Stress
Heat Exposure
Fever
Hyperthermia

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during the ramp protocol (up to 2.5 hours)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during the ramp protocol (up to 2.5 hours)

This trial's timeline: 3 weeks for screening, Varies for treatment, and during the ramp protocol (up to 2.5 hours) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Esophageal temperature rate of change

Predicted time until 40.2°C esophageal temperature

Predicted time until 40.2°C rectal temperature

+1 more

Secondary outcome measures

Esophageal temperature

Heart rate

Heart rate rate of change

+7 more

Other outcome measures

Esophageal temperature inflection point

Heart rate inflection point

Rectal temperature inflection point

Trial Design

4Treatment groups

Experimental Treatment

Active Control

Group I: Humidity-ramp protocolExperimental Treatment1 Intervention

Healthy male and female volunteers. Participants will complete all exposures. The humidity-ramp protocol will necessarily be performed first. The order of the fixed-condition exposures will be randomized.

Group II: Below-inflection fixed-condition exposureExperimental Treatment1 Intervention

Group III: Above-inflection fixed-condition exposureExperimental Treatment1 Intervention

Group IV: Control fixed-condition exposureActive Control1 Intervention

Do I qualify?Apply below to find out

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Who is running the clinical trial?

University of OttawaLead Sponsor

206 Previous Clinical Trials

266,129 Total Patients Enrolled

7 Trials studying Heat Stress

205 Patients Enrolled for Heat Stress

Robert D Meade, PhD, MPHStudy DirectorUniversity of Ottawa

Glen P Kenny, PhDPrincipal InvestigatorUniversity of Ottawa

7 Previous Clinical Trials

233 Total Patients Enrolled

6 Trials studying Heat Stress

193 Patients Enrolled for Heat Stress

Media Library

Humidity-ramp protocol Clinical Trial Eligibility Overview. Trial Name: NCT05963529 — N/A

Heat Stress Research Study Groups: Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure, Control fixed-condition exposure

Heat Stress Clinical Trial 2023: Humidity-ramp protocol Highlights & Side Effects. Trial Name: NCT05963529 — N/A

Humidity-ramp protocol 2023 Treatment Timeline for Medical Study. Trial Name: NCT05963529 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I qualify to participate in this trial?

"This clinical trial is open to any patient older than 18 and younger than 85 who has been diagnosed with heat stress. Up to 12 patients are needed for the experiment."

Answered by AI

Are participants aged 55 or younger eligible for enrollment in this research?

"This clinical trial is open to individuals aged 18-85 years old. Additionally, there are 1 trials specifically designed for minors and 5 studies dedicated to people over the age of 65."

Answered by AI

What is the total sample size of this research endeavor?

"Indeed, clinicaltrials.gov indicates that this study is currently trying to acquire participants. It was initially published on July 14th 2023 and has been amended in the past week with a total of 12 patients being requested from one medical centre."

Answered by AI

Are there any available slots left in this medical experiment?

"Affirmative. According to the clinicaltrials.gov records, this medical trial is actively enrolling patients and began recruiting on July 14th 2023; it was last updated on July 21st 2023. A total of 12 participants are being sought from a single location for this study."

Answered by AI

What are the chief aims of this investigation?

"The primary evaluation of this trial will be focused on the timeline until a 40.2°C esophageal temperature is reached at End-of fixed-condition heat exposure (hour 9 or termination). Supplementary objectives consist of examining rate of change in rectal temperature over the last two hours, predicting when a 40.2°C rectal tempature can be expected based off end-exposure readings and further assuming these trends remain constant, as well as gauging fluctuations in mean skin temperatures during the final 120 minutes of testing."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons

Glen P. Kenny 2023. "Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05963529.