Social Communication Growth Charts (SCGC) for Autism

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Marcus Autism Center, Atlanta, GAAutism+1 MoreSocial Communication Growth Charts (SCGC) - Behavioral
Eligibility
6 - 6
All Sexes
What conditions do you have?
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Study Summary

This trial is designed to find the most effective, cost-efficient treatment for young children with Autism Spectrum Disorder by comparing different parent and child interventions.

Eligible Conditions
  • Autism

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

20 Primary · 0 Secondary · Reporting Duration: 9, 12, 16, 21, and 30 months of age

Month 21
Autistic Disorder
Change in Autism Diagnostic Observation Schedule Score in Children Showing Signs of ASD
Change in Communication and Symbolic Behavior Scales (CSBS) Score in Children Showing Signs of ASD
Change in Measure of Active Engagement and Transactional Supports (MAETS) in Parents of Children Showing Signs of ASD
Change in Mullen Scales of Early Learning Score in Children Showing Signs of ASD
Change in Vineland-3 Adaptive Behavior Scales Score in Children Showing Signs of ASD
Communication and Symbolic Behavior Scales (CSBS) Score in Children Showing Signs of ASD
Measure of Active Engagement and Transactional Supports (MAETS) in Parents of Children Showing Signs of ASD
Mullen Scales of Early Learning Score in Children Showing Signs of ASD
Vineland-3 Adaptive Behavior Scales Score in Children Showing Signs of ASD
Month 30
Autistic Disorder
Communication and Symbolic Behavior Scales (CSBS) Score
Measure of Active Engagement and Transactional Supports (MAETS)
Mullen Scales of Early Learning Score
Vineland-3 Adaptive Behavior Scales Score
Month 30
Change in Autism Diagnostic Observation Schedule Score
Change in Communication and Symbolic Behavior Scales (CSBS) Score
Change in Measure of Active Engagement and Transactional Supports (MAETS) Score
Change in Mullen Scales of Early Learning Score
Change in Vineland-3 Adaptive Behavior Scales Score

Trial Safety

Trial Design

4 Treatment Groups

Usual care
1 of 4
Clinician-Implemented (C-I) Condition
1 of 4
Parent-Implemented (P-I) Condition
1 of 4
Social Communication Growth Charts (SCGC)
1 of 4

Active Control

Experimental Treatment

300 Total Participants · 4 Treatment Groups

Primary Treatment: Social Communication Growth Charts (SCGC) · No Placebo Group · N/A

Clinician-Implemented (C-I) Condition
Behavioral
Experimental Group · 1 Intervention: Clinician-Implemented (C-I) Condition · Intervention Types: Behavioral
Parent-Implemented (P-I) Condition
Behavioral
Experimental Group · 1 Intervention: Parent-Implemented (P-I) Condition · Intervention Types: Behavioral
Social Communication Growth Charts (SCGC)
Behavioral
Experimental Group · 1 Intervention: Social Communication Growth Charts (SCGC) · Intervention Types: Behavioral
Usual careNoIntervention Group · 1 Intervention: Usual care · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 9, 12, 16, 21, and 30 months of age

Who is running the clinical trial?

National Institute of Mental Health (NIMH)NIH
2,585 Previous Clinical Trials
1,984,468 Total Patients Enrolled
Emory UniversityLead Sponsor
1,527 Previous Clinical Trials
2,714,269 Total Patients Enrolled
Nathan Call, PhDPrincipal InvestigatorEmory University
4 Previous Clinical Trials
272 Total Patients Enrolled

Eligibility Criteria

Age 6 - 6 · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Your sibling has been diagnosed with autism and is receiving treatment at the Emory Autism Center of Excellence.
If you are an infant who shows early signs of autism and communication delay and did not respond to the first treatment, you cannot participate.
The child shows early signs of Autism Spectrum Disorder (ASD), as identified by a positive score on the Infant-Toddler Checklist (ITC) and at least two of the following autism screening tools: Early Screening for Autism and Communication Disorders (ESAC), Systematic Observation of Red Flags of ASD (SORF) Clinic, or SORF-Home.

Frequently Asked Questions

Is this research initiative currently accepting new participants?

"As per the information on clinicaltrials.gov, this medical trial is presently enrolling patients. This project was initiated on February 1st 2018 and has since been updated as of September 22nd 2022." - Anonymous Online Contributor

Unverified Answer

How many participants are accepted into this medical experiment?

"Affirmative. According to the clinicaltrials.gov repository, this research protocol is open for enrollment with a starting date of February 1st 2018 and an updated posting on September 22nd 2022. 300 individuals will be accepted from one medical site." - Anonymous Online Contributor

Unverified Answer

Is eligibility to join this trial open to me?

"This clinical trial is recruiting 300 participants, aged between 6 and 24 months, who have been diagnosed with autism spectrum disorder. In addition to this condition, they must also meet the following criteria: having an ASD sibling enrolled in the Emory Autism Center of Excellence; not responding to Stage 1 intervention (non-responders being infants displaying early signs of communication delay); exhibiting initial indications of ASD attested by a positive score on the Infant-Toddler Checklist (ITC) plus at least two results from either Early Screening for Autism and Communication Disorders (ESAC), Systematic Observation of Red Flags of ASD Clinic or SOR" - Anonymous Online Contributor

Unverified Answer

Is the recruitment process for this trial open to those aged 70 and above?

"According to the eligibility criteria for this study, infants aged 6 months old are eligible to participate and no upper age limit has been set." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.