PRIMeR for Autism Spectrum Disorder With Impaired Functional Language

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
IWK Health Centre, Halifax, Canada
Autism Spectrum Disorder With Impaired Functional Language+3 More
PRIMeR - Behavioral
Eligibility
< 18
All Sexes
What conditions do you have?
Select

Study Summary

Early intervention (EI) using naturalistic behavioural methods have shown benefits for the development of communication and other skills for young children with autism spectrum disorder. The publicly funded autism EI program in Nova Scotia (NS) is based on such a method, Pivotal Response Treatment (PRT), and pre-post studies indicate benefits for children and families. However, not all children benefit equally. In this study, the investigators test the efficacy of a brief parent-mediated intervention designed to prime responsivity to PRT in children with a minimal responder profile derived from previous studies of the PRT-based EI program.

Eligible Conditions

  • Autism Spectrum Disorder With Impaired Functional Language

Treatment Effectiveness

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Assessed at baseline, entry to EI program, and after 6 months of EI program

Month 6
Communication
Social initiations

Trial Safety

Trial Design

2 Treatment Groups

PRT
1 of 2
PRIMeR
1 of 2
Active Control
Experimental Treatment

40 Total Participants · 2 Treatment Groups

Primary Treatment: PRIMeR · No Placebo Group · N/A

PRIMeR
Behavioral
Experimental Group · 1 Intervention: PRIMeR · Intervention Types: Behavioral
PRT
Behavioral
ActiveComparator Group · 1 Intervention: PRT · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: assessed at baseline, entry to ei program, and after 6 months of ei program

Trial Background

Prof. Dr. Isabel Smith, MD
Principal Investigator
IWK Health Centre
Closest Location: IWK Health Centre · Halifax, Canada
2011First Recorded Clinical Trial
1 TrialsResearching Autism Spectrum Disorder With Impaired Functional Language
157 CompletedClinical Trials

Eligibility Criteria

Age < 18 · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have low levels of positive affect or limited positive and high negative affect.
You have a significant delay in cognitive abilities.
Parent or clinician report that the child has limited use of toys / objects.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.