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Children with asthma, parents/guardians of children with asthma, school staff for Childhood Asthma (CASCADE Trial)

N/A
Recruiting
Led By Anna Volerman, MD
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up years 1 and 2
Awards & highlights

CASCADE Trial Summary

Research has shown that adherence to evidence-based asthma guidelines leads to improved outcomes, yet critical gaps remain in the implementation of these guidelines, particularly among minority and low-income youth. Schools represent a crucial point of intervention, as demonstrated by school-based asthma programs that have addressed individual components of the guidelines with promising results. This project aims to develop, implement, and evaluate a pragmatic, multi-component asthma program that builds upon existing targeted interventions to fully implement the asthma guidelines and integrate them in school practices to foster sustainability. The investigator seeks to understand whether this type of program will improve asthma outcomes at the child and school level.

Eligible Conditions
  • Childhood Asthma

CASCADE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~years 1 and 2
This trial's timeline: 3 weeks for screening, Varies for treatment, and years 1 and 2 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Asthma control
Secondary outcome measures
Asthma impact - child
Asthma impact - parent
Asthma knowledge - child
+6 more

CASCADE Trial Design

1Treatment groups
Experimental Treatment
Group I: Children with asthma, parents/guardians of children with asthma, school staffExperimental Treatment1 Intervention
Children will be recruited from two University of Chicago Charter elementary schools. Children with a diagnosis of asthma and their parents will be eligible for inclusion in the study and will specifically be targeted for study recruitment. Staff and administrators at each school will also be recruited through in-person, phone, and email communication, primarily through word of mouth and professional development days. UCCS teachers, staff, and administrators will also be included in the program evaluation and we will obtain appropriate consent. Up to 400 families with a child/children with asthma from two UCCS schools will be added to a registry database. A total of 68 children with a diagnosis of asthma and their parents will be recruited for evaluation of the multi-component program, resulting in a total of 136 children and parents. We will also recruit 24 teachers, staff, and administrators across the two schools to participate in the evaluation of the overall program.

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Who is running the clinical trial?

University of ChicagoLead Sponsor
1,004 Previous Clinical Trials
819,377 Total Patients Enrolled
Anna Volerman, MDPrincipal InvestigatorUniversity of Chicago
1 Previous Clinical Trials
100 Total Patients Enrolled

Frequently Asked Questions

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~267 spots leftby Aug 2025