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Non-invasive Brain Stimulation

TMS for Epilepsy

N/A
Waitlist Available
Led By Aaron Boes, MD, PhD
Research Sponsored by Aaron Boes
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Must have the cognitive capacity to understand the risks and benefits of the study and provide consent
Neurosurgery patients (age 18 and above) who have implantation of intracranial electrodes
Timeline
Screening 3 weeks
Treatment Varies
Follow Up activity changes within seconds of the stimulation
Awards & highlights

Study Summary

This trial is testing the effects of a non-invasive brain stimulation (TMS) on human brains. Brain responses will be recorded to see if this treatment is effective.

Who is the study for?
This trial is for adults over 18 who are neurosurgery patients with intracranial electrodes implanted, undergoing long-term EEG monitoring for epilepsy surgery candidacy. Participants must understand the study's risks and benefits to give consent. Those with neurological or psychiatric conditions besides their primary disease are excluded.Check my eligibility
What is being tested?
The study examines how transcranial magnetic stimulation (TMS), a non-invasive brain stimulation method, affects brain activity as recorded by intracranial electroencephalography in patients preparing for epilepsy surgery.See study design
What are the potential side effects?
While TMS is generally considered safe, potential side effects may include discomfort at the stimulation site, headache, lightheadedness, or seizures in rare cases.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I understand the study's risks and benefits and can consent.
Select...
I am over 18 and have had brain surgery to implant electrodes.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~activity changes within seconds of the stimulation
This trial's timeline: 3 weeks for screening, Varies for treatment, and activity changes within seconds of the stimulation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in brain activity assessed with intracranial EEG

Trial Design

1Treatment groups
Experimental Treatment
Group I: TMS in patients with intracranial electrodesExperimental Treatment1 Intervention
We will administer TMS to neurosurgical patients with intracranial electroencephalography in order to better understand the effects TMS has on the human brain. Participants will receive both active and sham stimulation at varying points during the study.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial magnetic stimulation
2015
Completed Phase 4
~480

Find a Location

Who is running the clinical trial?

Aaron BoesLead Sponsor
1 Previous Clinical Trials
1 Total Patients Enrolled
Stanford UniversityOTHER
2,387 Previous Clinical Trials
17,334,020 Total Patients Enrolled
17 Trials studying Epilepsy
1,258 Patients Enrolled for Epilepsy
Aaron Boes, MD, PhDPrincipal InvestigatorUniversity of Iowa

Media Library

TMS (Non-invasive Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT03702127 — N/A
Epilepsy Research Study Groups: TMS in patients with intracranial electrodes
Epilepsy Clinical Trial 2023: TMS Highlights & Side Effects. Trial Name: NCT03702127 — N/A
TMS (Non-invasive Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03702127 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are additional participants being sought for this research?

"Data available on clinicaltrials.gov reveals that this medical test is no longer recruiting patients, having been first posted and last updated in 2019/2022 respectively. Nevertheless, there are currently 47 other trials looking for participants at the present time."

Answered by AI
~9 spots leftby Jun 2026