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Statistical Learning for Epilepsy

N/A

Recruiting

Led By Taylor J Abel, MD

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Normal hearing acuity in each ear (as determined by audiometric assessment)

Individuals 15-25 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during seeg-eeg recording sessions, up to 3 hours total

Awards & highlights

Study Summary

This trial is exploring how the brain processes speech by looking at the activity in the temporal lobe. This area is responsible for mapping acoustic information to linguistic representation and is difficult to study non-invasively. This trial will help researchers understand how the brain responds to different aspects of speech and how this response changes in different listening contexts.

Who is the study for?

This trial is for individuals aged 15-25 with epilepsy who are undergoing sEEG in the supratemporal plane and have normal hearing, vision, cognitive, and speech-language skills. They must be fluent English speakers without a history of autism or ADHD.Check my eligibility

What is being tested?

The study explores how the brain processes speech by examining responses to voice onset time (VOT) and fundamental frequency (F0) during routine clinical sEEG monitoring in patients with epilepsy.See study design

What are the potential side effects?

Since this research involves non-invasive observation during a standard clinical procedure (sEEG), there are no additional side effects associated with the interventions being studied.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My hearing is normal in both ears.

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I am between 15 and 25 years old.

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I am fluent in English.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during seeg-eeg recording sessions, up to 3 hours total

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during seeg-eeg recording sessions, up to 3 hours total

This trial's timeline: 3 weeks for screening, Varies for treatment, and during seeg-eeg recording sessions, up to 3 hours total for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Behavioral Impact of Change in Acoustic-Phonetic Dimensions

Behavioral Impact of Change in Listening Context

Supratemporal Neural Response to Change in Acoustic-Phonetic Dimensions

+1 more

Secondary outcome measures

Neural Response of Non-Regions of Interest to Change in Acoustic-Dimension

Neural Response of Non-Regions of Interest to Change in Listening Context

Trial Design

1Treatment groups

Experimental Treatment

Group I: Patient ParticipantsExperimental Treatment1 Intervention

This single-group study will recruit patients through the PI's clinical practice who are undergoing invasive neurophysiological monitoring (sEEG) with clinically necessary placement of electrodes in the supratemporal plane. All participants will complete the same behavioral response paradigms.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,722 Previous Clinical Trials

16,342,921 Total Patients Enrolled

1 Trials studying Epilepsy

National Institutes of Health (NIH)NIH

2,701 Previous Clinical Trials

7,506,851 Total Patients Enrolled

7 Trials studying Epilepsy

514 Patients Enrolled for Epilepsy

Carnegie Mellon UniversityOTHER

76 Previous Clinical Trials

539,905 Total Patients Enrolled

Media Library

Dimension-Based Statistical Learning Clinical Trial Eligibility Overview. Trial Name: NCT05209386 — N/A

Epilepsy Research Study Groups: Patient Participants

Epilepsy Clinical Trial 2023: Dimension-Based Statistical Learning Highlights & Side Effects. Trial Name: NCT05209386 — N/A

Dimension-Based Statistical Learning 2023 Treatment Timeline for Medical Study. Trial Name: NCT05209386 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research encompass those under the age of 65?

"This medical study requires participants to be aged between 15 and 25, inclusive."

Answered by AI

Is this medical research initiative still accepting participants?

"Affirmative. Clinicaltrials.gov attests that this trial, which was first created on May 2nd 2022, is actively recruiting patients. 25 participants are expected to take part in the study from a single site."

Answered by AI

Am I eligible to partake in this medical research?

"This clinical research seeks to recruit 25 individuals aged between 15 and 25 years, who present with aura. Furthermore, participants must satisfy the following criteria: English fluency; cognitive aptitude and speech-language proficiencies within the typical range (as confirmed by pre-operative tests); unimpaired visual acuity; sound hearing capacity in both ears (determined via audiometric evaluation); no prior diagnosis of autism or Attention Deficit Hyperactivity Disorder (ADHD)."

Answered by AI

What is the size of this research cohort?

"Affirmative. The clinicaltrials.gov webpage attests that this medical trial is presently searching for participants, with 25 needed from a single site since its inception on May 2nd 2022 and last update on October 18th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Flexible Representation of Speech

Taylor Abel 2022. "Flexible Representation of Speech". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05209386.

All > Epilepsy