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Behavioural Intervention
Exercise Training for Insulin Resistance
N/A
Waitlist Available
Led By Jill Kanaley
Research Sponsored by University of Missouri-Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Sedentary (not engaged in planned physical activities and performing less than a total of 2 h of physical activity per week during the last 6 months) men and women whose BMI is classified as obese (>30 kg/m2)
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 weeks
Awards & highlights
Study Summary
This trial will examine how exercise training affects glucose uptake into fat tissue in obese people, and if there are sex differences. #exercise #obesity #glucose #insulin #insulinresistance
Who is the study for?
This trial is for non-smoking, sedentary men and women who are obese (BMI >30 kg/m2) and have been weight stable in the past 6 months. They should not be on medications affecting metabolism or have cardiovascular disease, uncontrolled hypertension, orthopedic limitations, recent hormonal birth control changes, or pregnancy.Check my eligibility
What is being tested?
The study investigates how a 4-week exercise program affects fat tissue's ability to take up glucose in obese individuals. It aims to understand if regular physical activity can improve insulin sensitivity and overall metabolic health by focusing on changes in adipose tissue.See study design
What are the potential side effects?
Since the intervention involves exercise training, potential side effects may include muscle soreness, fatigue, joint pain or discomfort during the initial period of increased physical activity.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am not very active and my BMI is over 30.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 4 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
GLUT4 protein expression
TB1CD4 protein expression
Secondary outcome measures
percent body fat
Trial Design
1Treatment groups
Experimental Treatment
Group I: ExerciseExperimental Treatment1 Intervention
All subjects will undergo exercise training for 4 wks. 45-60 min of exercise, 4 sessions/wk supervised, 1 session unsupervised. intensity 60% of VO2 max
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
exercise
2014
Completed Phase 4
~1190
Find a Location
Who is running the clinical trial?
University of Missouri-ColumbiaLead Sponsor
361 Previous Clinical Trials
627,970 Total Patients Enrolled
20 Trials studying Obesity
2,178 Patients Enrolled for Obesity
Jill KanaleyPrincipal InvestigatorUniversity of Missouri-Columbia
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have recently changed your hormonal birth control.My high blood pressure is not managed without beta blockers.I have limitations in my bones or joints that affect my movement.I haven't smoked and my weight has been stable for the last 6 months.I am taking medication that affects my metabolism.I am not very active and my BMI is over 30.I have a heart condition.People who smoke.You need to sleep for 7-9 hours every night.
Research Study Groups:
This trial has the following groups:- Group 1: Exercise
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are the elderly being included within this trial's cohort?
"As specified in the trial's inclusion criteria, all participants need to be between 21 and 45 years of age."
Answered by AI
To whom is this trial open for enrollment?
"Aspiring participants must be between 21 and 45 years old, have obesity, and are anticipated to number about 24. These criteria will determine admission into the clinical trial."
Answered by AI
Are there any openings for enrollees in this experiment?
"Clinicaltrials.gov offers evidence that this particular trial is not actively seeking participants, as the last update to the page was on July 3rd 2023. Nonetheless, 1178 other trials are presently looking for candidates around the world."
Answered by AI
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